The title refers to the musical "How to Succeed in Business Without Really Trying" by Frank Loesser, Abe Burrows, Jack Weinstock, and Willie Gilbert that opened on Broadway in 1961. The original Broadway production of "How to Succeed in Business Without Really Trying" opened at the Forty-sixth Street Theater in New York on October 14, 1961, ran for 1417 performances and won the 1962 Tony Awards for the Best Musical and Book and was nominated for Best Score. Robert Morse (Winner of the 1962 Tony Award for Best Actor in a Musical), Rudy Vallee, Ruth Kobart and Sammy Smith recreated their stage roles for the movie version.
Copy of Time Magazine cover for July 23, 1965 can be seen on Darrin's magazine shelf in this April 6, 1967 episode.