Dwayne Johnson's character, Joe Kingman, suffers a separated shoulder that temporarily knocks him out of the big game. In real life, The Rock actually did suffered a season-ending shoulder separation while playing defensive tackle as a freshman at the University of Miami.
The scene in which "Joe Kingman" (Dwayne Johnson) runs the whole way through the city to the hospital carrying his daughter Peyton resembles Dustin Hoffman doing the same for his son in the movie Kramer vs. Kramer (1979). Also a movie about a father raising a child on his own.
Dwayne Johnson said he came up with the idea for his character to be such a huge Elvis fan, and suggested the idea to the writers, who loved it and added it to the script. Johnson later said that when they asked how he came up with the idea, Johnson responded that he is Elvis' biggest fan, and much of the Elvis memorabilia his character owns actually belongs to Johnson.
The Rebels and New York Dukes stand in for the NFL's New Enlgand Patriots and New York Giants. In the film, the Rebels play the Dukes in the last game of the regular season, and later in the League's Championship game. The movie was released during the 2007 NFL regular season, and in that season the Patriots played the Giants in both the last game of the Regular season and in Super Bowl XLII (2008).