According to Kevin Spacey, as part of their research for the film, they took some of the real players who was on the original team to Vegas. Although they weren't allowed to play, every time they wanted Spacey to up his bet, they would push up against his chair. He said, "I would win every time!"
The movie was used as a luxury prize for the contestants on the Big Brother (2000) 9 in the US. They played a competition involving blackjack, and the winners got to see a special advance screening of the movie. One contestant won a trip to Las Vegas worth $21,000, which included a three night stay at the same hotel the actors from the movie stayed in.
In one scene, Professor Rosa tells Ben he'll do well (at the heavily numbers-based task for which he's recruited him) because his brain is like a Pentium chip. This is a reference to the Intel Pentium microprocessor. Ironically, early versions of the Pentium processor had a bug where they would return incorrect results from arithmetic operations under specific conditions.