Towards the end of the movie, Charlie Wilson is presented with one of the Stingers he helped provide to the Afghanis. In an interview, the real Charlie Wilson said the Stinger is one of his most prized possessions, kept in "a very honored spot in my home."
In addition to the lifestyle portrayed on screen, Charlie Wilson had a DUI Hit-and-Run charge on the Key Bridge, outside Georgetown. He was never indicted; otherwise, he would have been far less successful securing money for his project in Afghanistan. The History Channel documentary about his life suggests that he drank that night (and other nights) to ease the pain he felt for the Afghan people.
Near the end, while Charlie Wilson is standing on the balcony with Gust Avrakotos during a party celebrating the defeat of the Soviet army in Afghanistan, Gust warns Charlie of future problems if he and the other members of Congress do not follow up on giving economic aid to the Afghani's. As Gust finished this warning, Charlie thinks about what he said, and you hear an airliner flying over Washington DC. It is an obvious, ominous reference to the 9/11 terrorist attacks on the Pentagon and the World Trade Center.
A vintage Miss Texas photo of Mary Nell Hubbard (1958) was used for a scene in the movie because Julia Roberts plays a former beauty queen. Hubbard wouldn't take payment for the photo she provided. She privately joked, "I've gone from a headline to an archive to an artifact," and her daughter gently teases her that she is a body double for Julia Roberts.
Charlie Wilson is invited to Joanne Herring's home for a party. In her house, we see a full length painting of her. Except for Julia Roberts's features, this painting is a copy of John Singer Sargent's "Madame X".
In one scene, Joanne (played by Julia Roberts) mentions that the campaign film she presented to Charlie wasn't a quality film to be submitted to the Golden Globes. Coincidentally, this film managed to get nominated in five categories at the Globes.