Dean, Castiel and Mary have a lead on Sam and set out to rescue him. Dean is uncomfortable putting Mary in danger, but she insists on going. Meanwhile, Crowley is tipped off that Lucifer has taken over the body of rock star Vince Vicente.
Sam and Dean investigate a case that leads them to a devout religious family living off the grid. They realize the parents are hiding a huge secret that could destroy them all. Meanwhile, Dean struggles to accept Mary's latest decision.
Lucifer realizes that as Vince Vincente, he can get his fans to do whatever he wants. Thrilled with this power, he arranges a VIP concert in order to kill them. Sam, Dean and Castiel enter the underbelly of the music industry to stop him.
After being arrested for the attempted assassination of the POTUS Sam and Dean must find a way out of a government detention facility in the middle of nowhere. Determined to find her sons, Mary and Castiel seek help from an unlikely source.