With the help of "squintern" Rodolfo Fuentes, the Jeffersonian team investigates the murder of a controversial conservative radio host whose remains were found in a storm drain. When the team discovers some of his extracurricular activities, they come across shocking evidence that narrows down the suspects. Meanwhile, Special Agent James Aubrey is desperate to gain the trust of Booth, and Brennan is worried about Booth's psychological well-being after recent events.
The Jeffersonian team, with the help Special Agent James Aubrey, investigate the murder of a video game designer whose remains were found washed up in a river. When the team uncovers more about the fortune the victim had acquired throughout his career, everyone who was close to him becomes a suspect. However, the investigation takes a turn when they discover that the victim was playing his own games on people. Meanwhile, "squintern" Jessica Warren enlightens the team about the educational cooperative with which she has been involved and Brennan and Booth discuss ...
Brennan gives a keynote speech at a convention for forensic scientists, who are all eager to help when the remains of a body are discovered in a stairwell, but the Jeffersonian team are stunned when Hodgins becomes a murder suspect.
The Jeffersonian team investigates the murder of an immigrant maid whose remains were found on the side of the road. The victim's wealthy former employer, Sandra Zins, is a key suspect in the case, but when the team discovers that the victim might have been brought into the country illegally, the team realizes the case is much bigger than it seemed. Amidst talks of marriage between Cam and "squintern" Arastoo, tensions rise between Brennan and Cam as Arastoo prepares his dissertation for Brennan's approval.
Avalon Harmonia lends her expertise when the remains of a psychic are found rotting in the trunk of a tree. But Hodgins is angered when she claims to see Sweets' ghost; and Angela is put in the middle of the crossfire. Booth and Brennan are divided about Christine's new imaginary friend; and the team remembers Sweets on his birthday.
When an affluent school teacher is found dead in an abandoned bookstore, the teachers and students at her school become suspects in the case. Meanwhile, Brennan's publisher encourages her to join Twitter to help grow her fan base, and "squintern" Jessica Warren teaches Brennan some tricks to master the Twitter-verse, skills Brennan enthusiastically puts to use.
When the body of an ex-con is found in pieces, the Jeffersonian team investigates a local bakery known for employing former felons. But they soon learn that the victim was involved in a robbery gone bad, and start targeting suspects from the ex-con's past. Meanwhile, "squintern" Arastoo Vazirir, must decide whether to return to Iran to visit his dying brother, which causes friction between him and Cam.
A miniature golf star's death reveals the sport's highly competitive nature. Meanwhile, Brennan is afraid that her dad is dabbling in crime again; and Wendell asks Hodgins to help him fix his girlfriend's family heirloom.
A high-stakes gambler's remains are discovered in an industrial shredder, but Booth's history of addiction comes into play when he and Brennan investigate the world of underground poker. Meanwhile, Hodgins invents a lab-related product.
A private high school student's remains are found in a ditch and bullying may have played a role in her death, but Brennan isn't so sure it's murder when she finds similarities between her own teen years and the victim's.
With only 48 hours before the execution of serial killer Alex Rockwell, whom Brennan and Booth helped convict, the Jeffersonian team must race against the clock to confirm Brennan's new suspicion that Rockwell may not have been responsible for those crimes.
Arastoo is kidnapped by a member of the Iranian parliament to help him with a murder case, so Booth and Cam head to the Middle East to expose the killer before it's too late. Meanwhile, Brennan is concerned about Booth's gambling habit, and asks Aubrey to protect her and Christine from her husband's bookie.
A cookie-jar collector's body is found near a river, and the killer may be a fellow kitchenware enthusiast. Meanwhile, Booth struggles to accept Brennan's decision to move out of their house due to his gambling addiction.