Nothing can get Earl out of his coma, so Randy turns to a young faith healer from their past. However, the boy says that he no longer heals people because he discovered how Earl lived his life after he "healed" him the first time.
Randy discovers that crossing items off Earl's list improves his condition, but the first item he chooses, returning a stolen motorcycle, brings back a frightening memory from Randy and Earl's past that Randy had forgotten.
The next item that Randy tries to cross off of Earl's list involves ruining their parents' vacation--by leaving a duffel bag full of marijuana they found in the bed of their truck at their parents' house, only to have them find it.
Billie starts her own list, and she and Earl help out a grocery store bagger whom they share on their lists. However, Earl soon discovers that Billie doesn't completely understand the concept of karma and The List.
Earl gives Joy a hot tub he found on the side of the road to cross an item off his list. However, Joy suffers an infection, and Crabman quarantines her in the trailer. As a result, Earl must perform Joy's daily chores.
Earl and Randy make amends for a depressed elderly man whose RV they stole years earlier. Their efforts fire him up enough that the man now wants to take revenge on another man who left him on the front line during the Korean War.
Earl finds out that he is no longer covered by the criminal code of ethics when someone steals Randy's birthday present from him. When he learns that the law of the underworld no longer protects him, Earl struggles with the idea of going to the police, despite Joy's protests that snitches are the lowest of the low.
Earl has a chance to cross two items off his list by throwing Joy's boys a Halloween party, and getting Randy a "little brother"--Catalina's nephew. But both could fail because everyone thinks Catalina's nephew is possessed.