| Julie Andrews | ... | Herself - Co-presenter: Life Achievement Award |
 | Reiko Aylesworth | ... | Herself |
| Hank Azaria | ... | Himself - Nominee for Outstanding Performance by a Male Actor in a Drama Series |
| John Drew Barrymore | ... | Himself - Memorial Tribute (archive footage) |
| Jason Bateman | ... | Himself - Nominee: Outstanding Performance by a Male Actor in a Comedy Series / Outstanding Performance by an Ensemble in a Comedy Series |
| Annette Bening | ... | Herself - Nominee: Outstanding Performance by a Female Actor in a Leading Role / Co-presenter |
| Richard Biggs | ... | Himself - Memorial Tribute (archive footage) |
| Cate Blanchett | ... | Herself - Winner: Outstanding Performance by a Female Actor in a Supporting Role: Co-presenter: Film Clip from "The Aviator" |
| Marlon Brando | ... | Himself - Memorial Tribute (archive footage) |
| Virginia Capers | ... | Herself - Memorial Tribute (archive footage) |
| Ray Charles | ... | Himself - Memorial Tribute (archive footage) |
| Thomas Haden Church | ... | Himself - Winner: Outstanding Performance by a Cast of a Motion Picture / Nominee: Outstanding Performance by a Male Actor in a Supporting Role |
| Glenn Close | ... | Herself - Winner: Outstanding Performance by a Female Actor in a Television Movie or Miniseries / Presenter: Outstanding Performance by an Ensemble in a Drama Series |
| Billy Concha | ... | SAG Spokeperson / Myself |
| Marcia Cross | ... | Herself - Winner: Outstanding Performance by an Ensemble in a Comedy Series |
| Steven Culp | ... | Himself - Winner: Outstanding Performance by an Ensemble in a Comedy Series |
| Jim Cummings | ... | Himself - Voiceover Actor (taped segment) |
| Rodney Dangerfield | ... | Himself - Memorial Tribute (archive footage) |
| Ossie Davis | ... | Himself - Memorial Tribute (archive footage) |
| Rosario Dawson | ... | Herself - Co-presenter: Outstanding Performance by a Female Actor in a Supporting Role |
| Drea de Matteo | ... | Herself - Nominee: Outstanding Performance by a Female Actor in a Drama Series / Outstanding Performance by an Ensemble in a Drama Series |
| Johnny Depp | ... | Himself |
| Portia de Rossi | ... | Herself - Nominee: Outstanding Performance by an Ensemble in a Comedy Series |
| Leonardo DiCaprio | ... | Himself - Nominee: Outstanding Performance by a Male Actor in a Leading Role / Outstanding Performance by a Cast of a Motion Picture / Co-presenter: Film Clip from "The Aviator" |
| Gary Dourdan | ... | Himself - Winner: Outstanding Performance by an Ensemble in a Drama Series |
| Jorja Fox | ... | Herself - Winner: Outstanding Performance by an Ensemble in a Drama Series |
| Morgan Freeman | ... | Himself - Winner: Outstanding Performance by a Male Actor in a Supporting Role |
| James Garner | ... | Himself - Recipient: Life Achievement Award / Nominee: Outstanding Performance by a Male Actor in a Supporting Role |
| Jennifer Garner | ... | Herself - Winner: Outstanding Performance by a Female Actor in a Drama Series |
| Paul Giamatti | ... | Himself - Nominee: Outstanding Performance by a Male Actor in a Leading Role / Winner: Outstanding Performance by a Cast of a Motion Picture / Presenter: Film Clip from "Sideways" |
| Mel Gibson | ... | Himself - Co-presenter: Life Achievement Award |
| Virginia Grey | ... | Herself - Memorial Tribute (archive footage) |
| Allen Lee Haff | ... | Himself |
| Julius Harris | ... | Himself - Memorial Tribute (archive footage) |
| Teri Hatcher | ... | Herself - Winner: Outstanding Performance by a Female Actor in a Comedy Series / Outstanding Performance by an Ensemble in a Comedy Series / Co-presenter: Outstanding Performance by a Male Actor in a Drama Series |
| Freddie Highmore | ... | Himself - Nominee: Outstanding Performance by a Male Actor in a Supporting Role |
| Felicity Huffman | ... | Herself - Winner: Outstanding Performance by an Ensemble in a Comedy Series |
| Howard Keel | ... | Himself - Memorial Tribute (archive footage) |
| Warren J. Kemmerling | ... | Himself - Memorial Tribute (archive footage) |
| Margot Kidder | ... | Lois Lane in Superman (1978) (archive footage) |
| Alan King | ... | Himself - Memorial Tribute (archive footage) |
| Linda Koopersmith | ... | Herself |
| Christine Lahti | ... | Herself - Nominee: Outstanding Performance by a Female Actor in Drama Series |
| Charles Lane | ... | Himself (taped segment in honor of his 100th birthday) |
| Cloris Leachman | ... | Herself - Nominee: Outstanding Performance by a Female Actor in a Supporting Role |
| Janet Leigh | ... | Herself - Memorial Tribute (archive footage) |
| Laura Leighton | ... | Herself |
| Virginia Madsen | ... | Herself - Nominee: Outstanding Performance by a Female Actor in a Supporting Role |
| Frank Maxwell | ... | Himself - Memorial Tribute (archive footage) |
| Virginia Mayo | ... | Herself - Memorial Tribute (archive footage) |
| Mercedes McCambridge | ... | Herself - Memorial Tribute (archive footage) |
| Debra Messing | ... | Herself - Nominee: Outstanding Performance by an Ensemble in a Comedy Series |
| Catalina Sandino Moreno | ... | Herself - Nominee: Outstanding Performance by a Female Actor in a Leading Role |
| Sophie Okonedo | ... | Herself - Nominee: Outstanding Performance by a Female Actor in a Supporting Role |
| Ron O'Neal | ... | Himself - Memorial Tribute (archive footage) |
| Jerry Orbach | ... | Himself - Memorial Tribute (archive footage) |
| Keke Palmer | ... | Herself / nominee |
| Sarah Jessica Parker | ... | Herself - Outstanding Performance by a Female Actor in a Comedy Series / Outstanding Performance by an Ensemble in a Comedy Series |
| Robert Pastorelli | ... | Himself - Memorial Tribute (archive footage) |
| Tony Randall | ... | Himself - Memorial Tribute (archive footage) |
| John Randolph | ... | Himself - Memorial Tribute (archive footage) |
| Ronald Reagan | ... | Himself Memorial Tribute) (archive footage) |
| Christopher Reeve | ... | Himself - Memorial Tribute (archive footage) |
| Tim Robbins | ... | Himself - Presenter: Outstanding Performance by a Cast of a Motion Picture |
| Eugene Roche | ... | Himself - Memorial Tribute (archive footage) |
| Geoffrey Rush | ... | Himself - Winner: Outstanding Performance by a Male Actor in a Television Movie or Miniseries |
| Isabel Sanford | ... | Herself - Memorial Tribute (archive footage) |
| Tony Shalhoub | ... | Himself - Winner: Outstanding Performance by a Male Actor in a Comedy Series |
| Nicollette Sheridan | ... | Herself - Winner: Outstanding Performance by an Ensemble in a Comedy Series |
| Carrie Snodgress | ... | Herself - Memorial Tribute (archive footage) |
| Imelda Staunton | ... | Herself - Nominee: Outstanding Performance by a Female Actor in a Leading Role |
| Jan Sterling | ... | Herself (Memorial Tribute) (archive footage) |
| Brenda Strong | ... | Herself - Winner: Outstanding Performance by an Ensemble in a Comedy Series |
| Kiefer Sutherland | ... | Himself - Nominee: Outstanding Performance by a Male Actor in a Drama Series / Outstanding Performance by an Ensemble in a Drama Series / Co-presenter: Outstanding Performance by a Female Actor in a Supporting Role |
| Hilary Swank | ... | Herself - Winner: Outstanding Performance by a Female Actor in a Leading Role / Nominee: Outstanding Performance by a Cast of a Motion Picture, Outstanding Performance by a Female Actor in a Television Movie or Miniseries |
| Peter Ustinov | ... | Himself - Memorial Tribute (archive footage) |
| Joe Viterelli | ... | Himself - Memorial Tribute (archive footage) |
| Ruth Warrick | ... | Herself - Memorial Tribute (archive footage) |
| Paul Winfield | ... | Himself - Memorial Tribute (archive footage) |
| Kate Winslet | ... | Herself - Presenter: Outstanding Performance by a Male Actor in a Supporting Role / Nominee: Outstanding Performance by a Female Actor in a Leading Role |
| Iggie Wolfington | ... | Himself - Memorial Tribute (archive footage) |
| Fay Wray | ... | Herself - Memorial Tribute (archive footage) |
