- Sex, drugs, and rock-and-roll will never be the same after a medieval sex drug makes a comeback on the college party scene. Everyone wants to try this "orgasm" drug but no one considers the side effects. This drug took its first victims in 1646. The church soon discovered that the blood-drained corpses found around the countryside were due to strigol, an elixir that made select victims thirst for blood. The drug wears off in hours, but while under its influence average men turn into animals. The church destroyed much of the strigol, or the vampire, but not all. And now, it's back. It's October 2004, and some college students are throwing a party at an abandoned farm to introduce their latest discovery, AYCE, a drug they promise is like nothing else. The one person who knows the side effects arrives too late. The bash becomes a bloodbath, and for the next few hours no one knows who will become the next victim or the next vampire.—PatDaddy J
- NOTE: Read SideFX as Side Effects, and the moral of this movie will fall into focus.
There's a new drug called AYCE on the University campus in Dallas, and party animal Matt [Todd Swift] can't wait to slip it into his friends' drinks at his super Halloween bash next Friday. Tuesday [Amanda Phillips], the girl with whom Matt is staying, doesn't want the party to be held at her house, so Matt is going to hold it at a secret location. If you want to go, you'll need to call him the morning of the party to find out where.
Like all good friends looking out for another friend's reputation, Erin [Christie Courville] and Andy [Ryan Fraley] suggest to Matt that they try some AYCE ahead of time, just in case it isn't all that great and Matt winds up looking like an idiot. So, that night they do some, and when Tuesday isn't looking, Matt slips some AYCE into her milk, too. The AYCE seems to make Erin super horny, so on the way home, she makes Andy stop the car. While they're kissing, Andy hears a noise outside the car, gets out to look around, and is attacked. [He is found later, his throat torn open. Police say that Andy was attacked by dogs. The news media suggest it might be a blood cult killing.] The AYCE gives Tuesday bad dreams. She awakens during the night, rushes to the bathroom, throws up what looks like blood, and calls her friend Shay [Amber Heard] to take her to the emergency room, where she throws up again. The doctor suspects drugs, maybe ecstasy or acid, and has the vomitus analyzed to see if it's really blood.
The next day, Matt takes a call from Tuesday's friend Monica [Marta McGonagle]. Erin has been taken to the hospital having some sort of nervous breakdown. Matt, Tuesday, and Shay pay her a visit, but when Erin sees Tuesday, she begins screaming until the doctor gives her something to knock her out. Later that evening, as Tuesday is studying in the library, she notices an old man watching her. A bit later, she sees him in the street, freaks out, and starts to run. He follows her, catches up, and grabs her. He promises not to hurt her if she'll just tell him where the AYCE is. She kicks him strategically and gets away.
The next morning, Tuesday wakes up to a telephone call from the doctor's office. Her lab tests have come back. It WAS blood that she was throwing up, only it wasn't her blood. She hears a noise outside the front door and opens it to find a note taped to the door. It says: "It makes you drink blood. Destroy it all before it's too late!! Meet me at Sunset Park." Suddenly, the old man is standing on her front porch. Tuesday slams the door in his face, but now it's all beginning to make sense. Tuesday wonders whether the blood she threw up might have been from killing someone and drinking his/her blood and that it's the AYCE that made her do it. That evening, Tuesday and Shay go to Sunset Park to look for the old man. Turns out his name is Carson Wilson [Chad Allen Black]. As a chemistry student at Berkeley in the 1960s, he re-invented AYCE...actually, RE-invented because the drug has been around since the Middle Ages and is the basis for the vampire legends in Romania and Bulgaria. AYCE is fermented from a rare, fungus-infected yeast and results in the ultimate high. It affects people in different ways. In some people, it makes them crave blood. Vlad Tepes was a notorious abuser of AYCE, he says. The church stamped it out, or so they thought.
Suddenly, Tuesday remembers that tonight is Matt's Halloween party where he intends to get everyone high on AYCE. The party is being held in an abandoned farmhouse. Tuesday and Shay race over. Tuesday tries to get Matt and his friends to listen to her, but they don't believe that AYCE is going to make everyone turn into vampires, until Monica kills Kendall by biting his neck and drinking his blood. They tie up Monica and intend to keep her that way for the next 12 hours, until the drug wears off. But the drug is already starting to affect others. One by one, they all become either vampires or victims. A virtual bloodbath ensues.
Epilogue: Another party, another time. Some guy is spiking drinks with AYCE as others are discussing how that Tuesday girl hacked everyone up with an ax. Tuesday, who is now confined to a padded cell, babbles over and over, "It wasn't me! It was the drug! It wasn't me! It was the drug!!" [Original synopsis by bj_kuehl]
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