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Side Effects (I) (2005)

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Ratings: 4.9/10 from 898 users   Metascore: 46/100
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A young woman fumbles with love and ethics as she navigates a career with one of corporate America's darlings...the pharmaceutical industry.

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Cast overview, first billed only:
Sandy Adell ...
David M. Ames ...
Dr. Jakobs (as David Ames)
John Apple ...
Plant Manager (as John L. Apple)
Ron Baumgartner ...
Business Man @ Plant
Collin Spencer ...
T. Bates (as Collin Bernhardt Spencer)
Bill Bolz ...
Scary Man (as William Bolz)
Stacy Brickson ...
Nathan Caracter ...
Tom Christianson ...
Dr. Michaels (as Tom Christensen)
Nathan Connor ...
Janet Cresson ...
Tom Curtis ...
David Durbin ...
Dan (as Dave Durbin)
Lee Ernst ...


Karly Hert is hired by the Braden-Andrews to work as pharmaceutical sales representative persuading doctors to prescribe drugs from Braden-Andrews. Karly feels a moral dilemma with her unethical job, but is seduced by the salary, car, bonus and benefits offered by the corporation. When Karly meets her former rep Zach Danner, they fall in love with each other. Karly gives herself a deadline of six months to quit her job and she decides to be honest with the physicians. The result increases the market share of Braden-Andrews and Karly is promoted; receives a BMW as an upgrade. When the anti-depressive Vivexx is approved by FDA, Karly finds that there are medical reports showing liver issues hidden by the industry. Karly is nominated by Braden-Adrews to the award Industry Rep of the Year and she needs to take a decision. Written by Claudio Carvalho, Rio de Janeiro, Brazil

Plot Summary | Add Synopsis


Love is a drug! See more »


Romance | Comedy | Drama


See all certifications »

Parents Guide:



Official Sites:



Release Date:

9 September 2005 (USA)  »

Also Known As:

Efeitos Colaterais  »

Filming Locations:

Company Credits

Production Co:

Show detailed on  »

Technical Specs



Aspect Ratio:

1.78 : 1
See  »

Did You Know?


Although unrelated to Steven Soderbergh's movie of the same name, both movies deal with the side effects of a fictitious anti depressant and the way the pharmaceutical industry deals with such issues. See more »


It seems that almost every time the one or more characters walks in front of a window, you can see the crew in the reflection, especially car windows. See more »


Arranged and Performed by Taylor Roberts Music
Written by Taylor Roberts
Courtesy of Taylor Roberts Music
See more »

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User Reviews

Worst Movie in a Long Time
9 November 2009 | by (Olathe, KS, USA) – See all my reviews

I was expecting a romantic comedy, perhaps with a predictable plot. All that to say, I wasn't expecting much. I got a lot less than not much.

All technical aspects of this movie are quite awful in a quite obvious way. The direction, editing, acting (except for Heigl), and soundtrack were deplorable. The romance was not developed. The tension between the characters was not revealed to any degree. There was no chemistry.

There were scenes that didn't belong and some scenes that we had to be mind readers to follow, because there was no dialog and no coherent acting skills to fill in the gaps.

It was a horrible mess.

2 of 3 people found this review helpful.  Was this review helpful to you?

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