The accompanying music for the first theatrical trailer is The Crystal Method's "I Know It's You". Milla Jovovich provides the vocals/wailing for the song, which was released three years earlier.
Claire Redfield's role in the movie is different than in the games. She leads a convoy of survivors across the dead desert, but in the games, she on a mission to find her lost brother Chris Redfield.
Raccoon City is clearly Detroit, Michigan from the graphic about 6-7 minutes into the film. The Detroit river and Belle Isle are clearly discernible, as is the half moon shaped industrial park to the North (towards the left in the film).
Sienna Guillory was offered the chance to reprise her role as Jill Valentine from Resident Evil: Apocalypse, but had to turn it down due to scheduling conflicts with Eragon and the character was then written out of this sequel.
The possibility of a third film in the franchise was first discussed when Resident Evil: Apocalypse opened at number 1 on the US box office, earning more than $23 million in its opening weekend.
Director Russell Mulcahy's chief insistence with this film - and its big point of difference over its predecessors - was that it be shot not at night but in blazing sunshine.
Temperatures would often be excess of 130 degrees on the Mexican locations. Various members of the crew frequently would have to be treated for dehydration.
The trivia item below may give away important plot points.
Detroit is not Raccoon City. Right around the Crow attack scene there is a reference to Alice escaping from the Detroit facility. The Umbrella Corporation has facilities in every major city.