The line that Isabella tells Sonny she got in a fortune; "life is short, time is luck" was previously used in the movie Heat (1995) in the scene where Neil McCauley is trying to convince Eady to leave with him. It was also used in Manhunter (1986) by Molly when talking to Will Graham.
Michael Mann had his actors train with real-life undercover law enforcement officers. Both Jamie Foxx and Colin Farrell observed undercover operations from a safe distance. Colin Farrell was told he'd learned so much, he was welcome to participate in a real sting operation. During the operation (caught on video, excerpts of which are shown in the DVD extra), guns were drawn and the officers identities questioned. Farrell reports being scared for his life. He spontaneously ripped open his shirt to demonstrate he wasn't wearing a wire, an act the agent-in-charge later commended for being realistic, quick-witted improvisation. After suffering anxiety and insomnia that night, Farrell contacted the agent-in-charge and was told that the sting operation was staged and that Farrell was never in any danger; he was to be told the next morning during a debrief.
During filming in Ciudad del Este (Paraguay) the crew came across bootleg and other illegal merchandise for sale in a similar fashion to that of the film's theme. Michael Mann purchased a copy of Collateral (2004) for two dollars while he was there.
Filiming in Miami took place during hurricane season. While filming a scene of Crockett and Tubbs driving in a Ferrari with the top down, a windstorm blew out the windows of a tall building. The glass damaged the car and just missed the actors. Another storm damaged the production office and delayed the filming of the ending.
Filming in Dominican Republic was suspended during October 2005 due to raucous behavior from the public and a shooting where the aggressor was injured. Jamie Foxx left the country and refused to work outside of the United States. This forced Michael Mann to change the original ending which was to be filmed in Paraguay.
In the scene in the Cuban bar, Sonny tells Isabella that his dad toured with a band that played music in the style of The Allman Brothers Band, because they made "THE music back then". This is a reference to the Miami Vice (1984) TV-series, and possibly also to Don Johnson, who was the original Sonny Crockett. In the pilot episode of the show, it is stated that The Allman Brothers Band is Crockett's favorite band. Don Johnson is a personal friend of the band, and in the 1970s, he co-wrote songs with now former The Allman Brothers Band guitarist/singer Dickey Betts, several of which were recorded by the band.
Crockett's car in the film is a Ferrari F430 Spider. In the TV series he drove a 1985 Ferrari Testarossa. The Ferrari Daytona Spyder that Crockett drove in the series' early days was really a fake Ferrari body on a Corvette chassis.
This movie, along with Heat and Collateral, all feature at one point or another, a white supremacist or supremacists. Waingro has various tattoos of his affiliation. Max, in Collateral, is robbed while tied to the steering wheel. Apart from their boots, quilted jackets, and generally all being Caucasian, the thug holding the gun to Max, has a small and faint swastika on the corner of his lower eye.
Tony Curran has a small role as the red-haired Aryan Brother. He is most noticeable, when Trudy is being filmed by the AB. He's the AB holding the camera in front of Trudy when she's detained in the trailer park.
Several of the firearms used in the film include the Barret M82A1 .50 sniper rifle, the Heckler & Koch G36C and G3A3 assault rifles, a Heckler & Koch HK69 40mm grenade launcher, a Benelli M4 Super 90 12-gauge semiautomatic shotgun, a SIG SG 552, a Remington M24 sniper rifle, and a Colt M4A1 carbine.
The watches, which Jamie Foxx (Ricardo Tubbs) wears, are a "Portuguese Chrono-Automatic" and an "Aquatimer Split Minute Chronograph" from the swiss watch manufacturer IWC (International Watch Company).