Dylan Sprouse and Cole Sprouse said in an interview, that their names on the show were actually named Dylan and Cole, as the characters were based around them, But as the story progressed, they changed their names as the twins' and the characters' personalities differed.
The Tipton Hotel where the show is set is supposed to be in Boston, Massachusetts. The hotel exteriors shown in the series are not actually the Fairmont Hotel in Vancouver, British Columbia, like some rumors say, but are computer generated.
The trivia items below may give away important plot points.
In season 1 episode 27 (Odd Couples) Lucas Grabeel was offered the role of Trevor but since the characters of Trevor and Maddie had to kiss the part was then given to Zac Efron given the brother and sister dynamic in High School Musical with Ashley Tisdale and Lucas Grabeel.