Yes, we have.
Creator David Shore based House on Sherlock Holmes because of his
ability to solve the medical mysteries of his patients. You'll find
lots of similarities to Holmes, who was in turn based on a real-life
doctor by Sir Arthur Conan Doyle, so it's come
In addition, Holmes and House have something else in common: both are
drug addicts. House is addicted to the painkiller Vicodin and
Holmes to injected
It should be noted, however, Vicodin, or Hydrocodone, is actually only a moderately powerful pain killing medicine. Tylenol 3, aka Acetaminophen with Codeine is the least powerful. Darvon or Darvocet, aka propoxyphene is the next least, and then you get to Vicodin, or Hydrocodone. There is, beyond that, in order of strength, Morphine, Percocet/Percodan, Oxycontin/Oxycodone (which is the main drug in the aforementioned Percocet and Percodan, but these come in higher doses), Methadone, Dilaudid, Demerol, and finally Fentanyl. Any and all of these can lead to addiction, however in people with no substance abuse history, use of these medications only lead to true addiction in under 1% of all users. Thus, Hydrocodone in significantly higher doses, especially the doses they made it appear House took, would not, under almost any condition, be the next step. Instead, they would just move to a more powerful drug.
Holmes,. OTOH, smoked opium, aka "chasing the dragon." FWIW, in the days Holmes used Opium, it was perfectly legal for him to do so both in the UK and the US.
The show is named after a play on words (House = "homes" = Holmes). House's best friend James Wilson is named after Holmes' friend John H. Watson. Both Wilson and Watson were three times married.
The man who shot House at the end of Season 2 is named "Jack Moriarty," who shares the surname of Holmes' archnemesis.
Holmes passed the time between cases by reading boring monographs; House passes time between cases by watching insipid medical dramas.
Does everyone also realize that their personalities are completely alike? Both are brilliant, arrogant, and single-minded in their pursuit of the answer to their mystery. The only difference is that Holmes is much more refined than House.
Arthur Conan Doyle partly based Sherlock Holmes on Dr. Joseph Bell, a lecturer at the University of Edinburgh, and eminent surgeon. (reference - Reader's Digest Strange Stories, Amazing Facts 1976, LCCC 76-2966, pages 554-555 - "The Incredible Dr. Bell")
In season 5 Episode 11 "Joy to the World", House receives a Christmas present that turns out to be a book on surgery written by Dr. Joseph Bell.
Also, in the season finale, House fakes his own death, as did Sherlock Holmes.