House is forced to choose a new staff... and gathers 40 applicants to start narrowing down the field. Meanwhile, an Air Force pilot wants House to treat her secretly so she doesn't ruin her chances of becoming an astronaut.
Down to 10 candidates for his team, House splits them into 2 groups to diagnose a patient whose short lifespan has been made even shorter. Foreman leads his own team to diagnose a patient at his new workplace.
A victim of a mugging presents with neurological symptoms and begins to mirror the behaviors of his doctors. Foreman joins the new fellows in seeking a diagnosis; Cameron and Chase takes bets on whom House will fire next.