Stan has a clone of Steve created so that he can have a competition with Francine to see who can raise him better. Meanwhile, Roger travels to Thailand to find Hayley and Jeff, and to get the reward money.
Stan's plan to out-do the neighbor's fancy haunted house backfires when Roger releases the serial killers he was borrowing from the CIA. Meanwhile, Steve faces Toshi's revenge when he takes a liking to his sister Akiko.
Roger helps Stan fulfill his dream of owning a family fun restaurant, but Roger later takes over the project and fires Stan, causing him to create his own rival restaurant.
After all of Francine's repressed memories come back to her, she decides to be a stand-up comedienne and gets her own sitcom. Meanwhile, Steve finds a female companion for Klaus, but he quickly grows tired of her.
Stan invites his half-Native American brother to his house every Thanksgiving to show off his wealth--until they visit him for Thanksgiving and discover that he's a multi-millionaire.
Stan and Steve accidentally shoot and kill Santa Claus, but he is brought back to life by his elves and is hell-bent on getting revenge against the entire Smith family.
Bored and disillusioned with her role as a housewife, Francine decides to take on a new identity. Meanwhile, Steve travels back in time to find a beautiful woman from a Nagel painting.
Stan and Francine make friends with a younger couple, but they can't keep up with their very active lifestyle. Meanwhile, Steve and Roger try to get a product refund over the telephone.
When Stan and Roger disagree over a recent string of events, Roger moves out of the house in protest but is quickly replaced by another warm body. After Roger learns of the replacement roomie, the two of them battle for Stan's affection. Meanwhile, Steve gets a new job at school that allows him to do a little self-promotion over the P.A. system.
Stan resorts to extreme and cruel measures to humiliate Steve and maintain his alpha-male status in the house, and Hayley and Jeff turn to Principal Lewis for marriage counseling.
In an attempt to advance in the CIA, Stan begins playing golf with Senator Buckingham. Things are going well until Roger accidentally sells the senator's daughter to a drug lord, forcing Stan must choose between family and his career.
When Steve has trouble crossing over into the "cool kids" social circle, Klaus and Roger place their bets to see how quickly Roger can make him cool. Everything they try backfires until Steve becomes the in-crowds designated driver. Meanwhile, Stan and Francine take turns pranking each other.
After Snot professes his love for Hayley and gets shot down, Steve and Roger devise a plan to cheer him up. Roger dresses up as Steve's cousin from New Jersey, Jenny Fromdabloc, and Snot falls hard for her. Meanwhile, Stan wants to live like a gentleman of the 1960s, complete with dark suits and dry martinis.
Stan spends some quality father-son time with Steve at the local zoo, but things go horribly wrong when Steve slips into a gorilla exhibit. Meanwhile, Roger bets Hayley that he can become a great Country singer and sets out to write the most heartbreaking song of all time.