Francine discovers that every one of their family vacations have been artificially experienced in tanks filled with green goo. This makes her very angry and she demands a real vacation. When they finally go on a real vacation Francine thinks this vacation must be fake too since it seems too good to be true. She therefore causes the family to suffer the consequences. Simultaneously, Roger attempts to become the greatest actor who ever lived.
Francine agrees to be the surrogate mother for their gay neighbors' child. But when the child is born, Stan kidnaps her and plans to take her to Nebraska, where he can legally keep the child away from them.
When StanÂ's mom gets dumped for the umpteenth time by a boyfriend, she comes running to Stan for support. Feeling threatened by her always-visiting mother-in-law, Francine is determined to cut StanÂ's umbilical cord and figure out what keeps going wrong with the men in her life.
After one of the wives of Stan's CIA coworkers tells Francine that her husband is missing, Francine tries to persuade Stan to be more open with her. He responds by telling her that he killed the husband.
With Francine gone to visit her parents, Roger holds a Spring Break blowout at the Smith house. During the festivities, Stan falls for a "Spring Break Buddy" and Steve is on the verge of losing his virginity.