The description of the Broken Butterfly is "A very powerful .45 magnum revolver. This will make anyone's day." is a direct reference to the famous dialogue in this film.
The plotline of the cop searching for a little girl while invesigating a pagan religion is used in Biohazard 4.
dr salvador, the large chainsaw wielding enemy in the village, is direct reference to leatherface
the garbage chute escape in chapter 5 is very similar to the groups escape from the detention area around the end of the second act of Star Wars
Dr Salvador wears a burlap sack over his head; identical to the one worn by Jason Voorhees
near the beginning of the game Leon is chased by a boulder just like the movie
The fog and forest in the begining, the Villagers move and act in a similar style to the deadites of the Evil Dead
The dogs with mutant tentacles is a direct reference to a similar scene in The Thing.
Description of the Broken Butterfly: "A very powerful .45 magnum revolver. This will make anyone's day."
the mine cart shootout in Chapter 4 is similar to the one in the movie.
Luis' death resembles Bishop's stabbing by the Alien Queen. Also, when Leon, Luis and Ashley barricade themselves inside a barn, Leon says "It's game time", just like Cpl. Hicks in this movie.
There is an item in the game named a Velvet Blue.
Krauser is identical in voice, facial structure, and facials scars to Tom Berenger's character in Platoon, Sgt, Barnes
In the "Mercenaries" bonus game, the playable character Jack Krauser can morph his arm into a mutated blob and attack; identical to the character Tetsuo in the anime film Akira.
The start screen of bonus game "Seprate Ways" Ada is seen posing the same way Nikita is posing on the movie cover.
One of the weapons is called the Hand Cannon.
The lead charecter name is Leon and there is a gun named Matilda.
Dialogue about shooting down a helicopter mirrors that in Metal Gear Solid.
Ashley says "Don't come" when being attacked.
Your first encounter with Ada, she takes off her sunglasses and they explode.
Spanish village, creepy villagers, and mutants
One of the villians, Ramon Salazar, shares his name with a 24 villian
Laser beams that Leon dodges later in the game are similar to the Red Queen's defences in the RE movie
The "popular" villains of the game are "infected" humans who all run off on the instinct to kill someone that is not infected.
There's a movie poster outside a movie theater, near the restaurant, advertising Biohazard 4.
A poster for this game entitled "Resident Evil 4" is on the wall in the game testing room.
At the Beginning you can find a Beer Stein as a reference to this game, because the first treasure you can find is a beer stein, However Sam only says "so the Zombies drink Beer"?
Leon's wearing his clothes from Resident Evil 4 game.
Chris makes reference to "those Ganados things in the Kennedy report".
Mentioned by Badger (as Resident Evil 4).
"And now it's Resident Evil 4."
GameCube version reviewed + footage used
the possessed Maxine plays this Wii game