After Evangeline has left with Aunt Adelaide, Nanny McPhee enters the children's room, and as she and Chrissie walk to the bed they pass Eric's, Lily's and Tora's beds, with the bare wood floor at the center - there is no rug. However, when Nanny McPhee leaves their room the long red and white rug is at the center of the floor, between all the beds.
When Eric, Tora and Aggy are getting ready for bed, Simon walks in and mocks, "And since when have we decided to do what we're told?" The towel to his right (viewer's left) is rumpled up, yet hangs straight in previous and following shots, then is rumpled again.
When Mrs. Blatherwick sits in the rocking chair in the kitchen, before the "mouse" races across the floor, in the first shot her left hand lies on her belly, with her right hand over her left, patting it gleefully. When it cuts to a close-up, her hands are in the opposite position.
When Nanny McPhee tells Cedric, "Lesson three, to get dressed when they're told is complete," he picks up a pen and fiddles with it. In the next close-up, Cedric's hands are clasped together, and a moment later he picks up the pen and fiddles with it.
Just before the wedding when Mrs. Quickly is talking to the children, she takes the rattle away from Aggie and breaks it in half with the handle in her right hand. In the next shot, the broken pieces have switched places and the handle is in her left hand. Then in two long shots, the handle has returned to the right hand.
During the food fight scene, Aunt Adelaide gets a slice of cake fired at her face, leaving a thick layer of light green color. Then next scene, Aunt Adelaide is walking away, and the frosting is a dark green color.
Throughout most of the movie, Sebastian is missing one of his front teeth. However, in the scene where he's hiding behind one of the chairs while his father and Mrs. Quickly have tea, his missing tooth has grown most of the way back in. Later in the movie, the tooth is missing again.
When the tarantula is crawling on Selma Quickly's hair, Cedric dives onto her. In the first shot his hands are around Selma's neck, as he is falling on top of her, but in the next shot his arms are wrapped around her waist with her arms dangling over his.
After Nanny McPhee and Mr. Brown discuss the subjects of Simon's cleverness and Evangeline's wellbeing with Aunt Adelaide, when Nanny McPhee leaves the room a crew member's movement is seen in the mirror over the mantle.
When Nanny McPhee seems to suddenly "appear" to Cook, after the children have gotten sick, you can see Nanny stand up from behind the counter, if you watch closely through the red bottle as the camera passes.
During the wedding scene, the priest is seen wearing a green stole. The proper colour stole for a wedding is white or gold. When the scene changes to snow and everything is white the priest is not wearing a stole at all.
In the end Tora is holding Agatha when the shot changes to show Nanny McPhee repairing the rattle, but when the rattle is given to Agatha, she is in her basket, even though the wedding is still going on.