A competitor is murdered during an "idiot run" shopping cart race in Central Park, and CSI suspects that a man found dead in a brownstone may have been murdered by a missing woman that he may have been holding hostage.
The death of a drag queen appears to be related to an old rape case involving a congressman, and two of the suspects in a second murder case are discovered to have used a professional alibi-providing company to conceal their affair.
A personal shoplifter supposedly turns murderer when a loss-prevention officer gets to close to her operation. Mac and Hawkes take a closer look at the death of a college student who was recently inducted into a secret fraternity.
A famous magician plans three death-defying stunts on three consecutive nights. But on the first two nights, two of his assistants die in ways that eerily resemble his stunts. Can CSI solve the mystery before there's a third victim?
At a French Revolution themed fund raiser at the UN, specifically at the French consulate, Mac, Stella and Hawkes find themselves hurdling diplomatic road blocks investigating two murders leading to an unexpected suspect. Meanwhile, Danny and Lindsay reunite on a "blinged" out cockroach that lead to murder of a prominent chef.
A body of a woman, Emma, in a black party dress is found in a dumpster. Her head is wrapped in packing tape. When the ME examines the body, he finds that her eye lids have been removed. This leads Mac to a recently released serial killer with the same MO. The second case possibly involves the Russian mafia. Lindsay and Danny team up to unravel the truth.
Detective Scotty Valens from Philadelphia's Cold Case unit comes to NY to investigate a murder that connects to Stella's past. Also Mac's recent solo bust is scrutinized because a handcuffed criminal fell of a rooftop.
The investigation to Mac's botched bust continues. Meanwhile, a guy who crashed his bride-to-be's bachelor party, is found dead in the restroom, and the eye witness testimonies point to tennis star John McEnroe.
An Irish gang sets an elaborate plot to reclaim a drug shipment being held at CSI after a bust, but Mac, Stella and Hawkes are forced to take them on. Meanwhile, Danny is being held as a hostage at another location by the same gang.
While Danny and Lindsay investigate a possible murder-suicide at a supposedly haunted house in Amityville, Mac and Stella tackle the case of a man who appears to have been killed after he already died.