Features a rare instance where Alfred Hitchcock refrained from making a lighthearted comment at the episode's end. Rather, he noted the seriousness of the episode's subject (alcoholism) and urged those affected by it to seek help.
In a long scene involving an advertising campaign presentation, actor Bill Raisch appears uncredited among the dozens of male clients in business suits who make up the audience. A few months after this aired, Raisch would become well-known to TV audiences as the infamous one-armed man in "The Fugitive" (1963 - 1967). Throughout the scene, Raisch holds a folder over the right sleeve opening of his suit coat to disguise the fact that he has no right hand...or arm.
Tony Randall and Jayne Mansfield starred together several years earlier in "Will Success Spoil Rock Hunter?" (1957). Randall's Rock Hunter also was an advertising executive.
"Hangover" is the only episode of the series based on two unique short stories: John D. MacDonald's 1956 "Hangover" (published in Cosmopolitan) and Charles M. Runyon's 1960 "Hangover" (published in Manhunt).