The image of Charlie Chaplin dressed as Hitler in the Time Machine.
Frito sings to himself: "Dun dun dun, Superman!"
fictional movie called "Ass" where the entire movie is a shot of some guy's ass (just like this Andy Warhol movie)
During "Monday Night Rehabilitation", the PA announcer states that the demolition derby vehicles are setting up Joe's car for the "Mallachi Crunch", a simultaneous collision from opposite directions. This was the signature move of the Mallachi Brothers and was attempted by them on Fonzie's derby car.
Years are counted off on screen as images of centuries passing are presented in the background, all while the main character sleeps.
After Joe escapes prison and is running down the street, he passes a burned out carcas of a DeLorean with the signature Back to the Future booster engines in the back.
The doctor in the beginning, when Clevon is in the hospital, mentions "...Doctors Krinsky and Altschuler..." which are both Executive Producers on Judge's show, King of The Hill.
references the chair Homer made that's a lounger + a toilet
the double d for double dose in Upgrayedd is lifted from a pimp in american pimp named rosebudd (a real pimp), and "the double d is for a double dose for this pimpin. "
President Camacho is depicted as a former Smackdown champion
joke where the U.N. is mispronounced as "the Un"
future earth with giant mountains of garbage - crop failure solved by hero finding sprouting plant
Strong Bad's line, "It's what plants crave!", refers to this movie, where a drink called Brawndo has the same slogan
Joe watches it on TV
accident results in man waking up in the 25th century, 500 years in the future, and becoming a hero (but everyone is dumber now)
"Ow My Balls" is a parody of "Jackass"