For the first time in seventy years, 20th Century Fox shipped prints of this movie without the final reel, which was shipped separately. This was done as a security measure as so people wouldn't be able to reveal the ending. To further ensure the safety of protecting the film's ending, security guards would hand-deliver the reel to theaters showing the film. Fox had individually numbered each reel, as well as a final security measure. Fox Executive Vice President and Sales Manager Richard Myerson stated it was "to ensure everyone's enjoyment of the film and to prevent 'spoilers', we've instituted extraordinary measures. We think it's worth the effort."
Famke Janssen is right-handed. However, she holds a gun in her left hand in this movie because she felt that because she's used guns before, she might look too comfortable holding it in her right hand.
Auditions were held for the part of Emily because Director John Polson hoped he would be able to "find another Dakota Fanning". Amongst the hopefuls were AnnaSophia Robb, but in the end, Dakota Fanning was cast.
At the dinner scene where Emily is presented books, the top book is Charlotte's Web. Dakota Fanning played Fern Arable, the main human character, in the live-action adaptation of the story, Charlotte's Web (2006).