The location for the drifting scene where the General Lee makes several laps around a monument is actually Lee Circle in New Orleans. In one shot, the camera angle is such that the statute of General Robert E. Lee, himself, appears to be looking down upon the General Lee as it passes.
After Cooter has had a visit from Rosco, he calls a friend of his by using the speed dial on his phone. The sound of the numbers being dialed is the same as the horn from General Lee after its makeover.
Twenty-six Dodge Chargers were used in this film. Several 1968 and 1970 Chargers were converted to look like 1969 Chargers. Only one Hemi Charger was used, the rest were 440s, 383s and a few small-block 318s.
In the original series, the Duke cousins used bows and arrows instead of firearms because they were on probation for moonshining. This was carried over into the film, but no explanation was that they were still running moonshine. Although the Duke cousins never used a firearm, this film had Smith & Wesson product placement. Sheev had an S&W cleaning mat on the counter when Roscoe came to his house. Bo and Luke carried the core samples into the lab in an S&W duffel bag.
After the success of the 'Starsky & Hutch' film, Ben Stiller and Owen Wilson were offered the roles of Luke and Bo Duke. Neither accepted the offer, as they did not feel it payed tribute to the original series as Starsky & Hutch did.
One of the original cars was used as a close-up car. It's a '68 Charger converted to look like a '69 and the original engine was replaced by a brand-new Hemi engine. The car was used for a few close-up scenes and then sent back to Warner Bros.
Seann William Scott openly regretted making the film. While most critics say it was too crude compared to the original, Scott actually felt that an R-rating would have "allowed me, Johnny and Jay to make a more enjoyable film."
In 2005, Warner Bros settled a lawsuit filed by representatives of film producer Bob Clark. Lawyers for the producer claimed that when the studio bought the rights to Clark's film Moonrunners (1975) in order to make The Dukes of Hazzard (1979) TV series, they bought the TV rights only, not the feature film rights. The lawsuit attempted to hold up release of this film. The settlement amount was reportedly $17.5 million.
While appearing on a Dutch TV talk show to help publicize her appearance as Daisy Duke in this movie, Jessica Simpson acted as a magician's assistant when she was sawed in half by magician Hans Klok in an illusion called "Clearly Impossible". In 1981, original Daisy Catherine Bach also took a turn at being a magician's assistant when she was sawed into six by magician David Copperfield in his fourth "The Magic of" TV special.