Sore from professional basketball, Nathan enjoys his first weekend home. Double date Chase enjoys Nathan's generous help with Mia. Haley happily dumped sonny-boy and his mate in mischief on Lucas and Peyton. They need parenting practice, but find even the best boys are too exhausting to just enjoy all day. Julian enjoys 'not quite a date' with Brooke. Now Brooke has identified Jack's brother and got him arrested as murderer, fostering veteran Sam tries to reassure or at least console Jack.
Nathan is on the bench during five losses, but has more maturity, team spirit and insight than the arrogant, selfish star scorer. He feels this is bound to pay off, as Dan predicts. After refusing six top directors, Lucas and Julian get an ultimatum from his father, Paul. He also tells Peyton that the infidelity she dumped Julian for was his publicity stunt. Julian is incredible patient with Brooke's insecurity. Chase is Mia's ideal playmate, inspiring a new single.
Julian and director Dixon, who enjoys the 'fringe (bed) benefits' to the fullest, press Lucas to make up his mind about casting. Their pressing for even more sexy actors/costumes then the originals stirs Brooke most. Nathan convinces coach Bobby Irons to field him instead of dumb selfish Devon, who still turns out to be a family man too. Dan enjoys coaching Jamie's 'first date', but the boy resents his teacher Lauren taking an adult interest in his mentor. Peyton bumbles trying to prep a childproof home. Haley braves the dictatorial new principal's threat to her job ...
Nathan can't be home on his wedding anniversary, so Haley comes to Charleston to arrange a romantic dinner in a run-down but charming townhouse. She proposes to move there so they can be together more, he generously suggests she starts touring again. Understanding lover Julian tries the L-word on Brooke, but that's still too soon. Meanwhile Jamie has a dinner guest which surprises nanny granny: grandpa Dan. Parenting memories first bring the exes together, then open up bitter wounds, how both are guilty of Keith's death. After Peyton's near-miscarriage, Lucas wants to...
Julian's dad is fired as studio boss, his projects therefore in doubt. Director Reese Dixon worries about saving pay and perks, masterly. Dan's heart finally arrives, but is lost in a doggish accident. Jamie demands the truth about Keith, but stays loyal. Sam sees Jack commit shoplifting and takes both loot and blame. Julian learns the truth and must decide whether to leave Tree Hill and Brooke. Haley may return as teacher if she publicly withdraws her support for Sam's article. She leaves to join Peyton's label as Mia's producer.
Julian offers Brooke tickets to move to L.A. with him and Sam. However, she keeps doubting and whining that she can't uproot Sam, although she's willing. Even Chase warns her not to waste such an opportunity. When Jamie asks about Keith, Nathan and Lucas take him to his auto-shop. Jack braves suspension to make all Haley's class walk out of Brumkin's boring English class. Even a college dorm PJ party can't console love-sick Mouth.
Nathan and Haley are considering a better school for genius Jamie, but doubt that academic excellence outweighs posh elitism and absence of sports. Nathan is expected to step up as leader - by coaching his ingrate rival Nino. Peyton has a car accident, which wrecks Lucas' Comet on wheels. Sam's boyfriend has found cool foster parents, and must leave Victoria expects Brooke to help save the company she stole, if not out of family loyalty then for the employees.
Nathan is offered a two year pro contract, but in Europe. He agonizes whether he should take it, as Bobby suggests, or stick to his NBA dream, as Haley advices. Jamie not only does well at his first school dance, he is the one who counsels 'babsitter' Skills to date his teacher there. While Peyton grumbles bedridden, Lucas repairs the Comet as a surprise, while both reminisce. Chase must convince Mia his affair with Brooke was and could only happen before them. Haley enjoys working with Nick Lackey, who wants her to produce music.
Warned by manager Bobby there's an NBA scout, Nathan and his protégé Nino perform excellently, then wait for a call. Lucas opposes Peyton preparing a 'posthumous' time-capsule and ask for a rushed marriage on account of her pregnancy risk. Nathan makes him reconsider and drops off Jamie with 'his uncle Keith'. Brook, Sam and Victoria are too busy to concentrate on Peyton's baby-shower or business. They are preoccupied as to whether Sam should be encouraged to spend time with birth mother Rebecca.
Hearing Nino, the player Nathan taught everything and made look good for the scout, got his NBA post makes Nathan consider giving up professional basketball. So he dodged training to attend Lucas's wedding, celebrated by Haley whom Lucas ordained by Internt for lack of a real minister. To Chase's pleasure, weddings make Mia frisky. Lucas invited Julian, but ignoring Brooke would be dateless he brought 'movie-brooke' Missy as date. To make them jealous, Brooke commandeers celebrity Nick Lachey.
Jamie's dream comes true: daddy Nathan finally gets an NBA post, with the Charlotte Bobcats. Peyton is hospitalized bleeding badly, but gives Lucas a healthy daughter and pulls trough. Julian stood by Brooke, then has great goodbye sex. Chase loves Mia enough to applaud her impending tour although it means being separated. Still terminal Dan visits retired coach Whitey Durham, considering suicide. Seeing newborn Sawyer restores his will to live.
The tree hill gang must learn that to live an exceptional life doesn't end once you've achieved your goals. With Lucas and Peyton gone, Nathan's a year into his NBA career, Haley has taken over Red Bedroom Records, and has to deal with the return of her free-spirited 26 year-old sister, Quinn. Brooke is still happy with Julian.
Brooke looks for a model as the new face of Clothes Over Bros. Mia and Haley fall short of selling a million records. Dan finds a confidant in an unlikely person. Nathan deals with being distant from the ones he loves, while Clayton reminds him he's in the NBA. Tree Hill's former bad girl - Rachel Gatina returns.
Nathan and Haley have to decide what to do about Renee's pregnancy claims as Clay thinks paying her off is the best way as it is Nathan's contract year. Mouth is asked by his station manager to investigate any titillating scandal about Nathan but decides not to tell his boss about the alleged pregnancy. Mouth and Skills come to an agreement about living together and Alex tests the patience of Millicent during a photo-shoot. Later she gives Julian a film script. Meanwhile, Quinn's husband David comes to find her when she won't answer his calls.
A disgruntled Renee makes her pregnancy known in the national media. Quinn tells David that she wants a divorce and spends the night with Clay. Mouth quits his job at the station after he is forced to report on the scandal surrounding Nathan. Brooke's fashion show is a huge success but Victoria warns her about Alex and Alex's obvious designs on Julian.
Julian gives Alex another chance and they continue to work on her script which he believes is very good but Brooke is not happy. Brooke reconnects with Chase to make Julian jealous and it works. Mouth gets to tell the truth on air about the allegations against Nathan much to his station manager's horror. Milicent begins to take weight loss tablets after Alex tells her she is a plus-size model. Elsewhere, Haley offers to pay off Renee unknown to her that Rachel and Dan have got to her first.
Dan and Rachel bring Renee onto his chat show. But does Dan have a few tricks up his sleeve? Meanwhile, Clay and Quinn reflect over their past loves - Clay and his late wife Sarah and Quinn and her earlier life with David.
Nathan, Julian, Mouth, Skills, James and Chuck go camping. Back in Tree Hill, Haley, Brooke and Quinn enjoy some "special" brownies. Meanwhile, Clayton continues to deal with his mourning issues and Dan has nightmares about a dying boy.
Haley returns to the stage much to Miranda's annoyance but the gig turns out to be a success and changes Miranda's attitude somewhat. Brooke believes she might be pregnant but is conflicted on how Julian will take the news - but the test proves negative. Julian finishes the script with Alex and heads out to be with Brooke at Haley's gig but gets a call from Alex telling him she's close to taking cocaine again so he goes to her much to Brooke's annoyance. Rachel and Dan arrive back in Tree Hill but his hoped reconciliation with Nathan doesn't materialize. But Dan isn't...
After losing his place on the Charlotte Bobcats Nathan reaches breaking point with Clay and fires him but this ends up causing a rift between Haley and Quinn with Quinn moving out to a hotel. Dan takes it badly that Clay messed up and tries to teach him a lesson by nearly drowning him in the surf. Later Clay is fired by his boss for stuffing up Nathan's contract. Victoria arrives unannounced and takes a liking to new TRIC bar manager Grubbs. Meanwhile, Brooke tells Julian that it is doubtful that she will ever be able to get pregnant and he promises to get different ...
Victoria bails Millicent out of jail the morning after her arrest and tells her to get herself together before she shows herself again. But Victoria is doubtful that Millicent has learned her lesson and proceeds to keep an eye on her and she is proved correct when Millicent steals a dress from Brooke's new collection to give to her model friend Makenna is exchange for a packet of blow. Mouth is distraught at the change in Millicent and they break up. Clay tries in vain to hold onto his one client but it is not to be and so he packs up his apartment much to Quinn's ...
Clay gets his mojo back with some help from Quinn and which might mean that Nathan can stay in the US and play in the NBA with the his old team the Charlotte Bobcats instead of going to Spain. Skills gets offered and takes the job in Los Angeles and brings Mouth along for the ride. Dan goes against Rachel on his television show and tells his audience that this is his last show and also serves with divorce papers. Julian rescues Alex from her near suicide bid and tells her the film deal is back on. Brooke fires Millicent from her model contract and tells her to get ...