When Nani tries to make everyone eat healthy Lilo activates an experiment that can cook up delicious food. She soon realizes the evil side effects of the experiments cooking but can Nani rescue Lilo and Stitch before its too late.
Lilo finds an experiment that allows people to skip 10 years into the future. Wanting to grow up and not be controlled by Nani she uses the experiment and things go from bad to worse as she realizes what happens each time she uses it.
Lilo finds an experiment that when worn resembles a crown and causes all others to obey their every command (except experiments designed after its creation) but she soon realizes that absolute power isn't as fun as it sounds.
Lilo Discovers an experiment designed to plan and execute mischievous practical jokes and uses it to get even with her substitute hula teacher who she thinks is out to get her but soon realizes that hes not as bad as she thought.
Crossover with American Dragon Jake Long Lilo and Stitch team up with Jake and friends to stop Gantu from capturing a shape-shifting experiment. Lilo tries to use the experiment to win a skateboarding contest to impress Kioni.
Lilo finds a wish granting experiment and tries to use it to make David more attractive to Nani in hopes of having a more normal family but runs into trouble with the experiments very literal interpretation of wishes.
With Lilo distracted Jumba and Pleakley are left to capture an experiment designed to create typhoon-like winds. Jumbas machine causes it to grow to a massive size they now have to figure out how to shrink and capture the experiment.
Lilo captures a bug-like experiment for her bug city but it has the ability to turn any living creature into a bug. She along with Stitch Jumba And Pleakley must have been turned and must find their way back before its too late.