Sybil and Kelly are shown lying together in bed. She unbuttons her shirt, he strokes her chest, and sex is implied.
Sybil and Kelly put Everett and Meredith in the same bedroom when they come to visit. They just assume that they are already sleeping together, and it does not even faze them, but it bothers Meredith, who refuses to sleep in the same bed with Everett in his parents' home.
Sybil makes a comment about how her youngest daughter, Amy, had a former boyfriend named Brad who "popped her cherry" (e.g. took her virginity). Amy is clearly embarrassed as her mother tells Meredith the story. Sybil says "The poor guy's still holding out. Guess he got a taste of something he liked". Later in the movie, Meredith gets drunk, meets Brad at a bar, and says "Aren't you the guy who popped Amy's cherry"?
Meredith wakes up after a long night of drinking in her fiance's brother's bed. It is presumed that she might not be wearing any clothes, although she is under the covers, so we don't see anything. She is horrified at the thought that she slept with Ben. It is later revealed that this didn't happen, but because of the alcohol, Meredith doesn't remember.
Amy and Brad start making out in a scene. Later, when her brother-in-law shows up, he asks his wife, "Who's the guy Amy's making out with in the ambulance"?
At a family dinner, Sybil starts talking about how she secretly wished all her sons would turn out gay, so they would never leave her. One of the sons, Ben, makes a casual joke, "I'm queer, I'm here"! Not understanding that they are all just joking (and a little drunk), Meredith questions Sybil about this, claiming that she doesn't believe any mother would actually want that for their child. Meredith openly states her opinion that people who are gay are "challenged" and that any parent would want their child to be "normal". This obviously results in a heated argument, and it may be offensive to certain viewers.