The title of the film, Gothika (can also be spelled gothica), is an unofficial term used to describe a form of purgatorial state of mind, a situation in which someone sees or feels things that no one else does and those who don't think those who can are crazy. They simply have a connection to the supernatural world.
Halle Berry was listed as a potential nominee on the 2004 Razzie Award nominating ballot. She was suggessted in the Worst Actress category for her performance in this film, she failed to receive a nomination however. The very next year though, she got a nomination for Worst Actress in the film Catwoman (2004) and won.
The trivia items below may give away important plot points.
This film was the first time John Carroll Lynch had portrayed a serial killer. The second time was when he played the suspected Zodiac Killer, Arthur Leigh Allen in the film Zodiac (2007). The third and fourth times where when he was cast as Twisty the Clown and John Wayne Gacy on the fourth and fifth seasons of the television series American Horror Story (2011).
The filmmakers attempted to have the film end back at the prison, including having a prison riot where Sheriff Ryan is killed by the inmates, but no one could figure out, story-wise, how to get Miranda back there, since she had already escaped from there twice earlier in the film. Director Mathieu Kassovitz ultimately decided that getting the characters out of the hospital for the climax was a good idea.