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The following FAQ entries may contain spoilers. Only the biggest ones (if any) will be covered with spoiler tags. Spoiler tags have been used sparingly in order to make the page more readable.
For detailed information about the amounts and types of (a) sex and nudity, (b) violence and gore, (c) profanity, (d) alcohol, drugs, and smoking, and (e) frightening and intense scenes in this movie, consult the IMDb Parents Guide for this movie. The Parents Guide for Van Helsing can be found here.
Van Helsing clearly states that he only kills monsters/creatures of evil. Frankenstein's Monster was not evil. Therefore he felt that he could not kill him even though, on several occasions, the monster asked him to.
During the final battle, Van Helsing kills Dracula when in his vampiric form. As Anna bursts into the room with the werewolf antidote, it is assumed that Van Helsing is on a rampage and leaps onto her probably causing her to die in the impact. She managed to inject him with the antidote before she died, causing him to transform back into a human and be cured. Van Hesling and Carl hold a cremation for her by the sea where she is at peace and with her family in heaven.
Anna's brother, Prince Velkan, shot it in the chest with a silver bullet before it went over the cliff. We can assume it changed back into a human, but either died from the bullet wound, or most likely, the fall.
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