Pancake claims to have come to Mississippi as part of the Freedom Riders movement in 1964. The Freedom Riders actually made their famous, eventful and at times rather violent rides, in the late spring and summer of 1961.
When Dorr is explaining their goings on in the basement, he says they hit a pocket of natural gas (which explains the explosions), knowing what it was by the smell of "rotten eggs". It is a known fact that natural gas has no smell naturally, but is in fact given it by the gas company so leaks can be noticed before they reach lethal levels.
Professor Dorr says the University of Mississippi is in Hattiesburg. It's actually in Oxford. The University of Southern Mississippi is in Hattiesburg. While it may be Dorr's error, it seems unlikely that Mrs. Munson, a Mississippi native, wouldn't notice.
Professor Dorr's orchestra "performs" both Renaissance and Rococo music. (The pivotal Luigi Boccherini recording is from the latter.) Although Dorr uses the terms interchangeably, the two styles are completely different, and separated by a span of about 150 years.
Mrs. Munson mentions her neighbor went down and bought a new stereo at the Costco in Pascagoula. Pascagoula is located on the Mississippi Gulf Coast near the Alabama/Mississippi state line - not on the Mississippi River. In addition, there is no Costco in Pascagoula, MS.
When Mrs. Munson is sitting in front of the painting at the very beginning of the movie, we see her knitting in an over-the-shoulder-shot and she wraps the wool round her fingers. When the camera changes, she does it again, although the wool actually is already wrapped around her hand.
At the beginning of the movie, we are looking through the eyes of Lump Hudson when a member of the other team approaches him. Before the ball is snapped, the crew is reflected in the other player's helmet.
The movie is set in a fictional town of Saucier, MS, which is along the Mississippi River and is the home of a riverboat casino. The real Saucier does not have a casino, is approximately 200 miles from the Mississippi River, and is located approximately 25 miles north of Biloxi, MS, in northern Harrison County.