The character of Jonathan Reiss exposes his private jet passengers to a form of Ebola. The "antidote" is a clear capsule with small black pills in it. In reality, this is a herbal medicine made in China and is a cure for an upset stomach.
In the scene where Lara Croft and partner jump off a building wearing "flying suits", called wingsuits, the stunt was performed by the two men who developed the suits. No CGI, wires, nets, or other SFX were involved. This suit was invented by Patrick de Gayardon, who died in a parachute accident in April 1998 while testing a new type of parachute in Hawaii.
The skin on Lara's upper left arm is rarely seen exposed in this film. Angelina Jolie sports a large tattoo on her upper left bicep which requires make-up to cover up. The fact her left arm is rarely bared in this film (her opening scene in a bikini is shot in such a way her RIGHT arm, not her left, dominates) may be due to criticism that the tattoo was sometimes poorly concealed in Lara Croft: Tomb Raider (2001).
In Lara Croft: Tomb Raider (2001), Angelina Jolie had to wear bra padding in order for her bust size to measure up to the videogame character's. Jolie wears considerably less (and possibly no) padding in this film, as the decision was made to give Lara more realistic dimensions.
Just as in the first film, there are several scenes in which the live-action Lara mimics the computer game version, in particular a scene in which she climbs around a pagoda and pole-vaults to a helicopter. She also takes a nasty fall as the animated Lara was prone to do.
In the film, Lara and Terry walk into a mall in Hong Kong called Times Square, after which they make their way to a then-unfinished taller building called the IFC tower. The film treats the two buildings as if they are attached, but in fact they are a subway train ride apart. The large skylight that looks up the IFC tower from Times Square was digitally added into the scene.
When fighting Chen Lo among the terracotta warriors, one is smashed and you can see that the head was a separate piece from the torso. This is factual,as they were initially created and fired separately before being assembled.
At the time of the film's release, Angelina Jolie said she had no desire to play the character a third time. Nonetheless, some planning for a third feature was undertaken until early 2004 when the studio announced plans for another Lara Croft film starring Jolie had been cancelled.