Following tradition (in both theatre and film), the actor portraying Captain Hook is the same actor portraying Mr. Darling (Wendy's father). In this case, it's Jason Isaacs.
With the exception of the Russian version, Piter Pen, this is the first live action adaptation of J.M. Barrie's story to feature a male in the role of Peter.
This is the first live-action sound film version of the story released to movie theatres. The Mary Martin versions Producers' Showcase: Peter Pan, Producers' Showcase: Peter Pan, and Peter Pan were preserved on kinescope and videotape, all for television, and the Mia Farrow version of Peter Pan was also shown on television in videotape format; though it features the same characters and setting, Hook was not considered a version of "Peter Pan".
Jeremy Sumpter went from 5 feet tall to 5' 8" during filming. The window of the nursery had to be rebuilt 4 times because the actor kept hitting his head on it.
According to Carsen Gray, when she's speaking to Hook, what she's saying is Iroquois for "You are the life-stealer. You are evil. You smell bad. You smell of bear-poop. You are many moons old and ugly."
"Jas." is a standard abbreviation for the name James which is why the sign on Captain Hook's cabin door reads "Capt. Jas. Hook". This is taken directly from the book. It is not, as many viewers assume, a reference to Jason Isaacs.
"Nana" was a Newfoundland, a breed particularly good with children, not a St. Bernard as used in the film. J.M. Barrie modeled Nana after his own dog, a Landseer Newfoundland. These dogs were very popular in Victorian England and were actually used to supervise children.
Liam Aiken supposedly was set for an audition for the role of Peter Pan, however a few days before the audition producers found out that Aiken was only 12 at the time. The producers were looking for a young actor aged between 14-17.
The trivia items below may give away important plot points.
An alternate, yet unfinished, ending was shot to match the one in the book in which Peter meets the adult Wendy (played by the narrator, Saffron Burrows) and her little daughter Jane.
WILHELM SCREAM: When the bubbly-faced pirate is shot by Smee and plummets into the ocean, immediately after Tinkerbell is discovered holding the crocodile in mid-air.