- Several endings were filmed in order to shroud the real conclusion in secrecy.
- The poem "As I was going up the stair / I met a man who wasn't there. / He wasn't there again today / I wish, I wish he'd go away" which one of the characters claims to have written when they were young, is really a poem by Hughes Mearns.
- There was some location shooting in Lancaster and other places in Los Angeles County, but the majority of the movie was shot on an enormous sound stage at Sony Studios in Culver City (the same studio that once housed the set for the Emerald City in The Wizard of Oz (1939)).
- Several film critics have noted the similarity of this film to the fictional film The 3 (a film within a film in Adaptation.)
- The book seen in Ed's car as he picks up Paris is "Being and Nothingness" by Jean-Paul Sartre.
- The complete names of the characters in motel are: - Edward 'Ed' Dakota - Samuel Rhodes - Paris Nevada - George York - Alice York - Timmy York - Larry Washington - Caroline Suzanne - Virginia "Ginny" Isiana - Lou Isiana - Robert Maine
- Frederick Coffin's last film.
- Though the dialog was removed, you can still see Ray Liotta say "I didn't do this" when he's face to face with John Cusack near the end.
- The film that Ginny (played by Clea DuVall) was referring to when she said: "Remember that movie where ten strangers went to an island and then they all die one by one and then turn out they were not strangers, they all had a connection?" is And Then There Were None (1945).
>>> WARNING: Here Be Spoilers <<<
Trivia items below here contain information that may give away important plot points. You may not want to read any further if you've not already seen this title.
- SPOILER: A life-size dummy was created to depict the murdered character played by Jake Busey, with a baseball bat lodged in his throat. One of the studio executives asked to keep the dummy as a souvenir, and stored it in his office closet. One night a cleaning woman opened the closet and was frightened out of her wits. The dummy was removed from the offices immediately after that incident.
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