Real logs were tested for the crash sequence, but they "didn't bounce enough", therefore, the logs are CGI in this film.
The accident on the highway was based on multiple accident on Interstate 75 in Ringgold, Georgia, on March 14, 2002, where were involved about 125 vehicles crashed and smashed into each other because a fog cut visibility to less than a car length. The accident killed at least four people and it injured at least 39 people, backing up traffic for miles.
An instrumental version of John Denver's "Rocky Mountain High", the song that accompanied most of the deaths in Final Destination (2000), plays in the dentist's waiting room.
(at around 5 mins) The school bus full of kids chanting "pileup" is from Mt. Abraham, the same school as all the victims from Final Destination (2000).
The Stonybrook Institution sanatorium that Clear places herself in is the same sanatorium used in the opening of Halloween: Resurrection (2002).
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