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Episodes cast for
"Ozzy & Drix" (2002) More at IMDbPro »

Season: 1 | 2
Year: 2002 | 2003 | 2004


Season 1


Season 1, Episode 1: Home with Hector

14 September 2002
When a mosquito bite transfers Ozzy and Drix into the body of a boy, Hector Cruz, another germ comes with them. It is up to Ozzy and Drix to capture this germ, Scarlet Fever, before it has disastrous consequences.

Jeff Bennett ... Drix (voice)

Phil LaMarr ... Osmosis Jones (voice)

Justin Cowden ... Hector Cruz (voice)

Jim Cummings ... Police Chief Gluteus (voice)

Tim Curry ... Scarlet Fever (voice)

Vivica A. Fox ... Ellen Patella (voice)

Pat Fraley ... Brain Advisor #1 (voice)

Kevin Michael Richardson ... Rescue Cell #1 (voice)

Alanna Ubach ... Mayor Spryman (voice)
Tasia Valenza ... Maria Amino (voice)

Season 1, Episode 2: Reflex

21 September 2002
Ozzy crashes his car into a nerve causing Hector's leg to fly out. Normally that wouldn't be much of a problem, but this time Hector accidentally tripped the local school bully, getting him into a fight after school.

Jeff Bennett ... Drix (voice)

Phil LaMarr ... Osmosis Jones (voice)

Justin Cowden ... Hector Cruz (voice)

Jim Cummings ... Police Chief Gluteus (voice)

Vivica A. Fox ... Ellen Patella (voice)

Pat Fraley ... Brain Advisor #1 (voice)

Rob Paulsen ... Travis (voice)

Neil Ross ... Cop (voice)

Alanna Ubach ... Mayor Spryman (voice)
Tasia Valenza ... Maria Amino (voice)

Billy West ... Muscle Cell (voice)

Season 1, Episode 3: Strep-Finger

28 September 2002


Brad Garrett ... Strepfinger (voice)

Phil LaMarr ... Osmosis Jones (voice)

Wendie Malick ... Sticky Flagella (voice)

Julian Sands ... Penicillin G (voice)

Alanna Ubach ... Mayor Spryman (voice)

Season 1, Episode 4: A Lousy Haircut

5 October 2002
Hector has head lice. As the authorities don't take the problem seriously Drix and Ozzy fights the lice on their own outside of Hector.

Vivica A. Fox ... Ellen Patella (voice)

Phil LaMarr ... Osmosis Jones (voice)

Jeffrey Tambor ... Mole (voice)

Alanna Ubach ... Mayor Spryman (voice)

Season 1, Episode 5: Oh My Dog

12 October 2002
As Hector finds a stray dog outside, an allergen is wrecking Hector's insides. The size changing allergen alternates between a huge monster and a meek guy. At the same time Drix finds a pet dog cell of his own.

Jeff Bennett ... Drix (voice)

Phil LaMarr ... Osmosis Jones (voice)

Justin Cowden ... Hector Cruz (voice)

Jim Cummings ... Police Chief Gluteus (voice)

Vivica A. Fox ... Ellen Patella (voice)

Rob Paulsen ... Travis (voice)

Alanna Ubach ... Mrs. Cruz (voice)

Season 1, Episode 6: Street Up

19 October 2002
Drix is getting tired of having no street smarts so he hires a teacher. The problem is who he chooses as his teacher, a criminal.

Danny Bonaduce ... Smirch (voice)

Phil LaMarr ... Osmosis Jones (voice)

Season 1, Episode 7: Gas of Doom

9 November 2002


Jeff Bennett ... Drix (voice)

Phil LaMarr ... Osmosis Jones (voice)

Justine Bateman ... Rota (voice)

Justin Cowden ... Hector Cruz (voice)

Rob Paulsen ... Travis (voice)

Tara Strong ... Jenna (voice)

Alanna Ubach ... Mayor Spryman (voice)
Tasia Valenza ... Maria Amino (voice)

April Winchell ... Lunchlady (voice)

Season 1, Episode 8: Where There's Smoke

16 November 2002
Hector has been hanging with the cool kids at school and tried smoking. This has brought in the addictive Nick O'Teen and his associates who want to enslave all cells in Hector.

Tim Curry ... Nick O'Teen (voice)

Phil LaMarr ... Osmosis Jones (voice)

Alanna Ubach ... Mayor Spryman (voice)

Season 1, Episode 9: The Globfather

30 November 2002


Phil LaMarr ... Osmosis Jones (voice)

Alanna Ubach ... Mayor Spryman (voice)

Henry Winkler ... Sal Monella (voice)

Season 1, Episode 10: Ozzy Jr.

7 December 2002
Strep-finger is back and he has a surprise for Ozzy: a parasite that grows inside him.

Season 1, Episode 11: Growth

1 February 2003


Phil LaMarr ... Osmosis Jones (voice)

Brian Posehn ... Sylvian Fisher (voice)

Alanna Ubach ... Mayor Spryman (voice)

Season 1, Episode 12: Sugar Shock

8 February 2003
Hector has been eating lots of sweets lately, causing his sugar levels to go out of whack. The energy dip afterwards has left all cells sluggish. At the same time, a large amount of bacteria has grown from all the sugar and have been raiding the sugar supplies.

Phil LaMarr ... Osmosis Jones (voice)

Jeff Bennett ... Drix (voice)

Justin Cowden ... Hector Cruz (voice)

Charlie Adler ... General Malaise (voice) (as Charles Adler)
Joe Lala ... Hector's Dad (voice)

Rob Paulsen ... Travis Lum (voice)

Jeffrey Tambor ... The Mole (voice)

Alanna Ubach ... Mayor Spryman (voice)
Tasia Valenza ... Maria Amino (voice)

Season 1, Episode 13: The Dream Factory

15 February 2003
Hector has been having a nightmare each night for a while. Ozzy and Drix has to prove themselves worthy to enter Hector's dreams and put an end to it.

Phil LaMarr ... Osmosis Jones (voice)

Kathy Najimy ... Loretta Epstein (voice)

Alanna Ubach ... Mayor Spryman (voice)

Season 2


Season 2, Episode 1: An Out of Body Experience: Part 1

23 August 2003


Phil LaMarr ... Osmosis Jones (voice)

Jeff Bennett ... Drix (voice)

Justin Cowden ... Hector Cruz (voice)

Vivica A. Fox ... Ellen Patella (voice)

Kevin Michael Richardson ... Rescue Cell (voice)

Alanna Ubach ... Mayor Spryman (voice)

Jim Cummings ... Police Chief Gluteus (voice)
Tasia Valenza ... Maria Amino (voice)

Kimberly Brooks ... Christine (voice)

Pat Fraley ... Pnuemoniac

Dawnn Lewis ... Cilia Tyson (voice)

Season 2, Episode 2: An Out of Body Experience: Part 2

30 August 2003


Phil LaMarr ... Osmosis Jones (voice)

Jeff Bennett ... Drix (voice)

Justin Cowden ... Hector Cruz (voice)

Vivica A. Fox ... Ellen Patella (voice)

Kevin Michael Richardson ... Rescue Cell (voice)

Alanna Ubach ... Mayor Spryman (voice)

Jim Cummings ... Police Chief Gluteus (voice)
Tasia Valenza ... Maria Amino (voice)

Kimberly Brooks ... Christine (voice)

Pat Fraley ... Pnuemoniac

Dawnn Lewis ... Cilia Tyson (voice)

Cree Summer ... Mayor Santorini (voice)

Season 2, Episode 3: Lights Out!

6 September 2003
Hector has a skating accident. The brain trauma leads to everyone inside Hector to forgetting who Ozzy and Drix are.

Jeff Bennett ... Drix (voice)

Phil LaMarr ... Osmosis Jones (voice)

Justin Cowden ... Hector Cruz (voice)

Jim Cummings ... Police Chief Gluteus (voice)

Pat Fraley ... Nerve Cell General (voice)

Rob Paulsen ... Travis Lum (voice)

Kath Soucie ... Naurine / Celly Katz (voice)

Alanna Ubach ... Mayor Spryman (voice)
Tasia Valenza ... Maria Amino (voice)

Frank Welker ... Dander (voice)

Season 2, Episode 4: The Conqueror Worm

13 September 2003

Season 2, Episode 5: Puberty Alert

20 September 2003
Hector is entering puberty. This manifests itself as an increase in testosterone. The hormone manifests itself as a gang of teenage hooligans who'd rather party than take responsibility. The hormones, lead by the charismatic Shane, has a rather different opinion on how Hector should act.

Jeff Bennett ... Drix (voice)

Phil LaMarr ... Osmosis Jones (voice)

Danny Cooksey ... Shane (voice)

Justin Cowden ... Hector Cruz (voice)

Jim Cummings ... Police Chief Gluteus (voice)
Joe Lala ... Hector's Dad (voice)

Hope Levy ... Brittany Estrogen (voice)

Rob Paulsen ... Backseat / Travis Lum (voice)

Alanna Ubach ... Mayor Spryman (voice)
Tasia Valenza ... Maria Amino (voice)

Season 2, Episode 6: Tricky Ricardo

27 September 2003
Maria's brother Ricardo appears. Maria considers him the family black sheep. As he tries to prove himself his past catches up with him.

Season 2, Episode 7: Aunti Histamine

4 October 2003
Hector has a runny nose, so he takes nose spray. The spray manifests itself as Drix's aunt Histamine. She effectively cleans up the snot, but Hector continues taking the spray, making her go nuts.

Jeff Bennett ... Drix (voice)

Phil LaMarr ... Osmosis Jones (voice)

Justin Cowden ... Hector Cruz (voice)

Jim Cummings ... Police Chief Gluteus (voice)

Andrea Martin ... Aunti Histamine (voice)

Rob Paulsen ... Travis (voice)

Alanna Ubach ... Mayor Spryman (voice)
Tasia Valenza ... Maria Amino (voice)

Frank Welker ... Dander (voice)

Season 2, Episode 8: A Growing Cell

11 October 2003


Phil LaMarr ... Osmosis Jones (voice)

Jeff Bennett ... Drix (voice)

Justin Cowden ... Hector Cruz (voice)

Charlie Adler ... Abglobtus Goop (voice) (as Charles Adler)

Season 2, Episode 9: A Cold Day in Hector

25 February 2004
Hector is out snowboarding, but gets lost outside in the cold. As if the body temperature loss isn't enough, the cold manifests itself as Cryo, a monstrous beast that shoots cold beams from its elbows.

Jeff Bennett ... Drix (voice)

Phil LaMarr ... Osmosis Jones (voice)

Justin Cowden ... Hector Cruz (voice)

Rob Paulsen ... Travis Lum (voice)

Susan Silo ... Cryo (voice)

Alanna Ubach ... Mayor Spryman (voice)
Tasia Valenza ... Maria Amino (voice)

Season 2, Episode 10: Supplements

14 June 2004
Hector accidentally inhales paint dust. The dust manifests itself as a team of super villains called the lead heads. To combat them Drix summons The supplements, a super hero team composed of vitamins and minerals.

Season 2, Episode 11: Double Dose

21 June 2004
Ozzy performs osmosis as he sleeps. This leads to the creation of a mutated twin that is all but law abiding.

Season 2, Episode 12: Nature Calls

28 June 2004


Jeff Bennett ... Drix (voice)

Phil LaMarr ... Osmosis Jones (voice)

Justin Cowden ... Hector Cruz (voice)

Rob Paulsen ... Travis Lum (voice)

Alanna Ubach ... Mayor Spryman (voice)
Tasia Valenza ... Maria Amino (voice)

Frank Welker ... Billy Blob Bile (voice)

Season 2, Episode 13: Cavities

5 July 2004
General Malaise escapes from prison and takes over one of Hector's teeth.

Phil LaMarr ... Osmosis Jones (voice)

Jeff Bennett ... Drix (voice)

Justin Cowden ... Hector Cruz (voice)

Charlie Adler ... General Malaise / Dr. Hammertoe (voice) (as Charles Adler)

Alanna Ubach ... Hector's Mom (voice)

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