The further adventures of Osmosis Jones and Drix as they defend the body of a young boy.




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Series cast summary:
 Osmosis Jones (26 episodes, 2002-2004)
 Mayor Spryman / ... (22 episodes, 2002-2004)
 Drix (14 episodes, 2002-2004)
 Hector Cruz (14 episodes, 2002-2004)
 Maria Amino (11 episodes, 2002-2004)


OZZY & DRIX, based on the breakout characters from the feature film "Osmosis Jones," is an animated inner-body, buddy-cop comedy which follows the adventures of white blood cell cop Ozzy and his partner, over-the-counter cold pill Drix, as they defend the City of Hector, the body of a 13-year-old boy. The second season of Ozzy & Drix amplifies their infectious humor with Ozzy's in-your-face antics and Drix's knowledgeable yet clueless wit as they continue to take on whatever comes their way, regardless of how small or simple a situation may appear in the outside world of Hector. Only they know what really happens "skin deep" and what it takes to always be on 24-hour alert, whether it be the sprouting of Hector's first whisker, a rowdy encounter with the Testosterone gang, an unexpected appendicitis attack or the long-awaited visit from Drix's Auntie Histamine. With their headquarters behind Hector's cornea, these partners have established their "private eye" agency... hoping to keep ... Written by Kurt Kongtong <>

Plot Summary | Add Synopsis






Release Date:

14 September 2002 (USA)  »

Also Known As:

Ozi i Driks  »

Company Credits

Show detailed on  »

Technical Specs


(26 episodes)

Sound Mix:


See  »

Did You Know?


The title is short for Osmosis and Drixonol. See more »


[Hector has eaten too much sugar and all the white blood cells, except The Mole are tired and Drix wants to know why, but The Mole refuses to answer]
The Mole: Whoever found out about my secret adrenaline supply......
Drix: You have a secret adrenaline supply?
The Mole: Who told you this? They will suffer!
Drix: You told me!
The Mole: Oh, yes, well maybe I could let myself off with a warning...but NO! I must be punished! No one crosses The Mole, not even, The Mole!
[The Mole gives himself a wedgie]
The Mole: Let that be a lesson to me!
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Follows Osmosis Jones (2001) See more »

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User Reviews

Clever, original and smart spin-off show
8 June 2010 | by (United Kingdom) – See all my reviews

I am aware that the movie Osmosis Jones does have a fairly bad rap, but when I saw it I was surprised at how much I enjoyed it. This spin-off show Ozzy and Drix actually surpasses it I think. The concept is still fresh, clever and original, and I really liked how smart and entertaining it was. Yes, some of the humour is crude and there are one or predictable moments at times. However, the animation does have its uniqueness with nice backgrounds and the characters look interesting, and the music is good, even the theme song was tolerable and admittedly I don't like that style of music. The characters are likable and unique, Drix is my favourite, he's funny and cute if somewhat silly on occasions. I also like Ozzy because he is cool and smart, and the supporting characters are quirky too. The voice acting is also top notch. Overall, clever, original and smart spin-off show that in my opinion is better than the film. 9/10 Bethany Cox

3 of 4 people found this review helpful.  Was this review helpful to you?

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