In the scene where Wang fights Rathbone's guards, they are constantly making sure that no priceless antique urns are broken. This is the same exact action by Jackie Chan's character in the climax of Rush Hour.
Artie Doyle looks nothing like the real Arthur Conan Doyle, who was a plump man with bushy mustache. However, Artie does possess a striking resemblance to Sherlock Holmes himself, especially according to the famous Sidney Paget's illustrations.
During the fight with the ruffians, Jackie falls into a coffin. The sign on the wall behind him reads "Sowerberry". Mr. Sowerberry is the funeral Director/Mortician from the book Oliver Twist. During this scene the first four notes of the theme to "The Addams Family" are heard.
Director David Dobkin had a difficult time choosing a suitable Asian actress who could do movement work, emote well and speak decent English. He then saw clips of Fann Wong's videos Wo lai ye (2001) and Qing she yu bai she (2001) and requested to audition her in London, which she did attend. She subsequently got the role and her number of scenes was increased by 30%.
When Artie Doyle tries to break the lock of Madame Tussaud's, Roy compares his work to that of a surgeon. This is probably a reference to the fact that the real Arthur Conan Doyle was a physician, even though in the movie he's a detective.
When Roy is fantasizing about his future family life, he mentions his kids' names as "Vera, Chuck, and Dave." These are the names of the grandchildren in Paul McCartney's fantasy from the Beatles song, "When I'm Sixty-Four".
The scene where Chon Wang gives Doyle Roy's watch to see what can be learned from it is a direct allusion to Sir Arthur Conan Doyle's "The Sign of Four" when Watson gives Holmes his watch to see what the great detective can induce from it.
Alison King who played Carla Connor in Coronation Street (British TV Soap Opera), she did appear in the very short scene when Owen Wilson was in the bedroom and answered the door inside an adult building.