There are five survivors in a futuristic library. Bam is their supreme dictator, and has the others interrogated and tortured, believing them to have said where. What Bam means is unclear, but he distrusts all.
Hamm is blind and unable to stand; Clov, his servant, is unable to sit; Nagg and Nell are his father and mother, who are legless and live in dustbins. Together they live in a room with two windows, but there may be nothing at all outside.