Many of the supporting parts are played by supporting actors from Dune (2000), recast into different characters. For example, Korba is played by Karel Dobrý who previously portrayed Dr. Liet Kynes, and Klára Issová, who played Lichna, appeared as a Fremen housemaid in the Atreides palace.
According to interviews, Alice Krige was John Harrison's first choice to play Jessica in Dune (2000), but was unavailable. However, Saskia Reeves had to back out of this miniseries because of pregnancy, so Krige was re-offered the part.
James McAvoy would later star in another screen adaptation of a fantasy novel. "The Chronicles of Narnia: The Lion, The Witch and The Wardrobe", which is based on the book by C.S. Lewis. "Children of Dune" is adapted from the novel by Frank Herbert.
After finishing work on the mini-series, James McAvoy would do voice work on the 2004 Danish fantasy drama film "Strings", which in that film McAvoy provided the voice of the film's lead protagonist Hal Tara, a prince whom leaves his city to avenge his father The Kahro of Hebalom, whom he believes was assassinated by a tribe of warriors called The Zeriths and falls in love with a Zerith warrior woman named Zita. Leto II (McAvoy) is the son of Emperor Paul Atreides (Alec Newman) whom avenged his assassinated father Duke Leto Atreides (William Hurt) and falls in love with a Freman woman named Chani (Barbora Kodetova) whom is Leto II's mother.
Chani dies giving birth to Leto II and Ghaniama. "Dune" was one of George Lucas's influences behind the "Star Wars" films. In "Star Wars: Episode VI - Return of the Jedi" Princess Leia is revealed as Luke Skywalker's twin sister and is the daughter of Anakin Skywalker, the Jedi Knight, believed to be the chosen one in a Jedi prophecy whom became Darth Vader and that they were separated at birth and in "Star Wars: Episode III - Revenge of the Sith", Anakin Skywalker's wife Padame Amidala dies giving birth to Luke and Leia.