Shortly after the defeat of Doctor Octopus and his symbiont army from the previous game, super-villain Electro attacks New York using high powered weaponry that'll turn him into a god, leaving Spider-Man to save the day.
Did You Know?
At the end of the video game, The Mighty Thor is credited with defeating Electro in the final battle. This is because Thor was supposed to appear in an video segment in the video game where he talks with Spider-Man shortly after he has defeated Hyper-Electro, thus giving Thor the credit with Electro's defeat in the Daily Bugle newspaper. This was removed because the game's original ending takes place atop the World Trade Center towers when the game was being developed and it was removed because of the towers' destruction on 9/11. See more
[while fighting Spider-Man
None of your meddling!
Spidey crawls up a building saying things about the crew. See more