Eleven teams of two people travel from downtown Los Angeles, California to Valparaiso, Chile, where they battle exhaustion, and have to face their fear of heights in one of the most daunting Road Blocks ever.
The nine remaining teams travel from Puerto Varas, Chile to Bariloche, Argentina. Some people become physically exhausted at one of the Detour choices, while at the other option, others find it mentally challenging to follow directions in a search for buried loot.
In the rest period, a bus takes the eight teams from Hamburg, Germany to an unknown location in France, from where they travel to Massiges and find that their nerves are tested by a re-enactment of the First World War at the Detour. When a Blind U-Turn comes into play, one team finds that their cocky attitude may cost them dearly.
The six remaining teams travel from Pierry, France to Praslin, Seychelles, where some race with a giant tortoise at the Detour, and one person from each team searches for a message at the bottom of the sea at the Road Block.
The four remaining teams travel from Singapore to Shanghai, China. For the first time, teams have to perform two Road Blocks in a single leg, with each person in the team having to do one of the two tasks.
With the million-dollar prize on the line, Racers come face-to-face with Darth Vader, and Teams drop all pretense of friendliness after a cut in line cuts into another Team's time while an angry confrontation awaits another at the finish line.