Loom (1990 Video Game)
The seagull from LOOM appears (this is mentioned in the title credits)
Guybrush asks LeChuck whether he still remembers Bobbin Threadbare, the protagonist of this game.
In "Current Status", Strong Bad has a floppy disk of this game
In the Scumm bar, there's a pirate who looks identical to Cob, a character from Loom, with a badge that says "Ask me about Loom". Also, at one point in the game, Guybrush suffers an injury to the head and temporarily loses his memory. When he regains consciousness he says, "I am Bobbin Threadbare. Are you my mother?", which is a repeated line in LOOM.