In the middle of a crushing heat wave, Andy is confronted with the ethical dilemma of whether to help a single woman, pre-destined to have early Alzheimer's disease, have a baby. Also, Lu fights to save a sixteen-year old girl who has been shot in a gang initiation and finds out the truth about a mother who turns in her daughter with Downs Syndrome as the perpetrator of the shooting. Andy struggles with introducing Dr. Milo Morton to her daughters. Elsewhere, Andy and Milo stop a baby's heart in the fight to save its life.
When Andy encounters a young woman with amnesia and her fiance, she must decide which secrets should remain untold. Meanwhile, when a pregnant patient refuses to stop using drugs, Lu faces an ethical dilemma and must decide whether to intervene.