After finding a new dead body, Langston and Brass uncover a connection to an unlicensed doctor who may be "Dr. Jekyll." Meanwhile, Willows discovers that two women found dead in a hotel were con women who preyed on an unsuspecting actuary.
Hodges and Wendy pose as CSIs to impress a group of "Crime Cadets" and get some help in solving a crime, and Hodges becomes jealous when Henry asks Wendy out. Meanwhile, Nick and Greg solve a bacteria outbreak at the police station.
A comic who was one-half of a legendary Vegas duo from the 1970s is found dead on the eve of their reunion show, while the body of a fugitive who bombed an abortion clinic is dumped in Las Vegas with over 100 bullet holes in him.
The crime lab reluctantly brings in imprisoned serial killer Nate Haskell after he claims to know the identity of "Dr. Jeckyll." Meanwhile, clues revealing his next and perhaps final victim are mailed to Dr. Langston.
Nick accidentally stumbles upon a badly decomposing dead body in the home of a mother with a severe hoarding disorder, but that is only the first of a number of grisly surprises the team finds in the house.
A college student suffers a death at the hands of an animatronic dinosaur from a Las Vegas show, while the death of a man whose daughter and friend disappeared years ago is tied a new lead on the locations of their dead bodies.
The death of a casino hotel guest is tied to an unlikely sexual encounter with a married woman in the room next to his, and a cat and a parrot may hold the clues of their owners' apparent double homicide.