CSI investigates the death of a toddler who was left in a cardboard box in a parking lot. A registered sex offender who is wrongly accused threatens Catherine after the real cause of death is identified.
A temperamental sitcom actress is found dead in her Las Vegas hotel room, and there are plenty of suspects. Soon afterward, her photo double is also killed, this time in Hollywood in the dead actress' car.
A woman's unlikely suicide is tied to a bank robbery and a hypnotist, the team investigates the murder of a guidance counselor who was also a degenerate gambler, and Sara helps out in an euthanasia case.
When CSI investigates a homicide that appears to have connections to the S&M world, Gil turns to Lady Heather for help. But is he really there because of his personal problems with Sara and not for the actual case?
A man blames the anonymous sender of emailed death threats after his wife and daughter are shot. Two teens in a convertible crash into a tree; one has an inexplicable shoulder injury. Grissom attends a transfer hearing.
When a new murder leads to a connection with an infamous serial killer, Grissom secretly joins the class of well-known criminal pathologist Dr. Raymond Langston to gain access to the killer and get a crack in the case.