While Ecklie fights for his life after his shooting, Russell's patience begins to wear thin as the team tries to get to his kidnapped granddaughter before she is killed.
A female acquaintance of Greg is killed, and it appears to be related to an old Vegas legend about a mobster who murdered a musician back in the 1960s.
A reverend is found dead on former CSI detective Warrick Brown's grave, and the team discovers several connections between the case and Brown and his family.
A mass gravesite in the desert has an unlikely connection to an accused serial killer in Seattle from detective Findlay's past, but how far will she go to bring him to justice?
While working a foot patrol on the strip, the CSIs stumble on a murder victim, and a number of their suspects are already in police police custody on lesser charges.
While the team tries to solve a murder tied to counterfeit wine, Mac Taylor from the New York crime lab comes to Las Vegas for his girlfriend's convention, only to discover that she has disappeared.
While investigating the brutal homicide of a teenage motocross driver, the team stumbles upon a man and his daughter living in mysterious underground bunker.
The murder of a brother and sister and a pair of home invaders is part of a complex revenge plot, and a man is burned alive in the trunk of his own car.