Will Gaffney, stand-in for David Morse, was killed in a freak accident when a truck on which he was riding suddenly turned and drove off a cliff while being filmed in Quito, Ecuador. The movie is dedicated to him.
Kessler's bible is used for two maps of the area. The main map is drawn over Luke 21-22, which talks about the return of the Son of Man (Thorne will come and save Peter Bowman). The second map has a passage marked out, Matthew 5, which discusses the wrongness of revenge and loving your neighbor.
Originally it was planned that all extras were to receive the normal pay used for American extras. But the Ecuadorian government, who could not afford to have their actors paid that well demanded that the movie pay Ecuadorian salaries.
During the scene at 1:40 into the movie when he says, "these guys are my Panama crew", you can see a piece of cardboard on the wall behind with "JUST CAUSE" written on it. Operation Just Cause was a U.S. invasion of Panama to capture Manuel Noriega, military leader and drug criminal - a storyline very similar to the movie's plot.