A wealthy animal collector wants Hunter Pierre to go after and hunt Wildmouse in a ghost town. Molasses Droopy and Thunderbolt McWolf are baseball players with Miss Vavoom as umpire and Dripple as pitcher.
Droopy and Dripple are new star attractions at a circus. Bromo the Fearless Bear attempts to outperform them. Tom and Jerry go up a beanstalk and have to escape the giant with a golden egg. Droopy and McWolf race in a footrace.
Calaboose Cal and Tom are hired by a penthouse owner to get rid of Jerry. Scoundrel McWolf is accused of taking sheep from loyal sheepdog Dripple and Miss Vavoom. An army of red ants crash Tom's birthday and cut the cake into pieces.
Jerry shows Tuffy how to be a musketeer and has sword fights with musketeer Tom. Dark Wolf uses a Super Sucksaforsarurus to inhale the universe and it's up to Droopy and Dripple to stop him. Spike and Tyke's basket is under ant attack.
Droopy Man and Dripple Boy go after Dr. Reginald Riff Rat who plans to turn the city into rats just like him and kidnapped Cheetah Vavoom. Wildmouse escapes the police with Jerry's help who later steals Tom's love interest in the end.
In the old west, Sheepherders Droopy and Dripple protect a sheep from Sidewinder McWolf and his henchman. Calaboose Cal shows his inventions Tom in order to capture Jerry. Calaboose Cal has to get rid of a termite.
Droopy and Dripple are the Right Brothers set to compete for $20,000 dollars against Flip Flop McWolf. Tom buys roller skates and has trouble skating. Jerry has the same skates but has no problems skating.
Droopy and Dripple compete in an archery contest with McWolf and his son Stinky. Tom is sent to deal with the fire-breathing Wildmouse because the knights are too scared. Calaboose Cal becomes a magician for a child's birthday party.
McWolfenstein creates a bride for himself, but when she sees Droopy coming, she falls madly in love with him and takes off with him to an amusement park. Tom's hillbilly cousins pop in for a visit and help him get Jerry.
Slap-shot Droopy and Ice-pick McWolf play hockey. Miss Vavoom is the ice queen and Dripple is the hockey referee. A hawkeye bird is after both Tom and Jerry. An angel cat tells Tom that he is on his 8th live and has to be careful.
Droopy and Dripple play against McWolf and his son, Stinky at the Volleyball Championship. The winner will get $100,000 and a date with Volley Vavoom. Tom and a hunter are after Wildmouse. Tom and Jerry are off to go into a space shuttle.