The opening sequence in the film was originally supposed to take place on a boat. During a location scout, they found the airplane set and decided to revise the script. As it turns out, the original boat sequence was originally inspired by the airplane sequence in Twilight Zone: The Movie (1983).
The sequence with Lisa (Jacinda Barrett) was filmed months after principal photography was completed. It was decided after the film was done that a death scene needed to occur much earlier in the film. This is why the character is never mentioned before or after her appearance. Anson Mount actually had to wear a wig during this sequence because he had cut his hair significantly since.
Since the campus used as Alpine University in the film didn't have an actual bell tower, a 150 ft. tower was built at an estimated $150,000.00. All of the interiors were done on a separate stage and the actual bell was papier-mâché.
Jessica Cauffiel's character Sandra prior to her on-set death urban legend was to appear as a coma patient on ER. Ironically fellow female main character and film victim Vanessa Valdeon portrayed by Eva Mendes appeared on an episode of ER.