Peter starts betting on Chris' baseball games when Chris becomes a pitcher to work on his anger management issues. In the meantime, Brian and Stewie re-team with Frank Sinatra, Jr. to start an Italian restaurant.
Peter is set to have a vasectomy against his will, but has an accident at the sperm bank, which causes Stewie's rival sibling to be born. Meanwhile, Lois gains weight after an angry Peter refuses to have sex with her anymore.
Brian's gay cousin Jasper comes to town for a visit to see Brian. Jasper brings with him a man he wants to marry, but Mayor West is trying to ban gay marriage to distract everyone from a financial scandal.
When Joe buys a new home theater system, Peter gets jealous and decides to build a multiplex movie theater in his back yard. But while doing so, he finds a human skull. It begins haunting the Griffin house, and Stewie gets sucked through a portal into the realm of the dead.
When burglars break into the house, the Griffins take cover in the attic where they discover Peter has built a 'panic room'. They go in it, and Peter tells them about his history. They send Meg for food but the burglars catch her. The rest of the Griffins stay behind and Peter accidentally floods the room and they're going to drown. Luckily Joe gets them out and we find out Meg has been accused of sexual harassment by the burglars.